Csnk1d - casein kinase 1, delta Gene

Mus musculus

Also known as 1200006A05Rik; D930010H05Rik

Gene ID: 104318 | Gene type: protein coding

About Csnk1d

Summary

This gene encodes a member of the Casein Kinase I (CKI) family of serine/threonine protein kinases. A highly similar human protein regulates an array of cellular processes by influencing the Wnt and Hedgehog signaling pathways. The encoded protein may also be involved in the regulation of Apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Csnk1d Products(4)

mRNA	Protein	Name
NM_027874.3	NP_082150.1	casein kinase I isoform delta isoform 2
NM_139059.3	NP_620690.1	casein kinase I isoform delta isoform 1
NM_027874.3	NP_082150.1	casein kinase I isoform delta isoform 2
NM_139059.3	NP_620690.1	casein kinase I isoform delta isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19414593	MGI
enables protein kinase activity	IDA IDA: Inferred from direct assay	10848614	MGI
enables protein kinase activity	IGI IGI: Inferred from genetic interaction	17244647	MGI
enables protein kinase activity	IMP IMP: Inferred from mutant phenotype	29191835	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in circadian regulation of gene expression	IMP IMP: Inferred from mutant phenotype	19414593	MGI
involved in midbrain dopaminergic neuron differentiation	IGI IGI: Inferred from genetic interaction	17244647	MGI
acts upstream of or within non-motile cilium assembly	IMP IMP: Inferred from mutant phenotype	24648492	MGI
involved in positive regulation of Wnt signaling pathway	IGI IGI: Inferred from genetic interaction	17027228	MGI
involved in positive regulation of non-canonical Wnt signaling pathway	IGI IGI: Inferred from genetic interaction	17244647	MGI
involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IMP IMP: Inferred from mutant phenotype	19414593	MGI
involved in protein phosphorylation	IDA IDA: Inferred from direct assay	19414593	MGI
involved in protein phosphorylation	IGI IGI: Inferred from genetic interaction	17027228	MGI
involved in protein phosphorylation	IMP IMP: Inferred from mutant phenotype	21930935	MGI
involved in regulation of circadian rhythm	IMP IMP: Inferred from mutant phenotype	19414593	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	19414593	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

casein kinase I isoform delta

casein kinase I

CKI-delta	CKId
tau-protein kinase CSNK1D

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-148233S	JNJ-6204		/	Unkown
HY-RS03246	CSNK1D Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21113	Csnk1d Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27632	Csnk1d Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Csnk1d	NCBI	NCBI:1453

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