Hscb - HscB iron-sulfur cluster co-chaperone Gene

Mus musculus

Also known as Hsc20

Gene ID: 100900 | Gene type: protein coding

About Hscb

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in [2Fe-2S] cluster assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in sideroblastic anemia. Orthologous to human HSCB (HscB mitochondrial iron-sulfur cluster cochaperone). [provided by Alliance of Genome Resources, Apr 2022]

Hscb Products(2)

mRNA	Protein	Name
NM_001359835.1	NP_001346764.1	iron-sulfur cluster co-chaperone protein HscB isoform 2 precursor
NM_153571.2	NP_705799.2	iron-sulfur cluster co-chaperone protein HscB isoform 1 precursor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in primitive erythrocyte differentiation	IMP IMP: Inferred from mutant phenotype	32634119	MGI
involved in primitive hemopoiesis	IMP IMP: Inferred from mutant phenotype	32634119	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

iron-sulfur cluster co-chaperone protein HscB

HscB iron-sulfur cluster co-chaperone homolog	J-type co-chaperone HSC20
iron-sulfur cluster co-chaperone protein HscB, mitochondrial

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06386	HSCB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22204	Hscb Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hscb	NCBI	NCBI:150274

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