2. Gene
  3. CASR - calcium sensing receptor Gene

CASR - calcium sensing receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa

Also known as PCAR1

Gene ID: 100520980 | Gene type: protein coding

About CASR

Primary_assembly 13: 138,280,364-138,364,252 reverse strand.Sscrofa11.1:CM000824.5

This gene has 2 transcripts (splice variants), 203 orthologues and 12 paralogues. Biased expression in kidney (RPKM 4.2), ovary (RPKM 1.4) and 2 other tissues.

CASR Products(1)

mRNA Protein Name
NM_001278748.1 NP_001265677.1 extracellular calcium-sensing receptor precursor

CASR Protein Structure

PBP1_CaSR

PBP1_CaSR: cd06364 (32 - 529)

NCD3G

NCD3G: pfam07562 (547 - 600)

7tmC_CaSR

7tmC_CaSR: cd15282 (620 - 645)

7tmC_CaSR

7tmC_CaSR: cd15282 (620 - 871)

7tmC_CaSR

7tmC_CaSR: cd15282 (657 - 678)

7tmC_CaSR

7tmC_CaSR: cd15282 (687 - 711)

7tmC_CaSR

7tmC_CaSR: cd15282 (735 - 751)

7tmC_CaSR

7tmC_CaSR: cd15282 (778 - 804)

7tmC_CaSR

7tmC_CaSR: cd15282 (812 - 835)

7tmC_CaSR

7tmC_CaSR: cd15282 (840 - 865)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1089 a.a.
Protein Preferred Names Protein Names

extracellular calcium-sensing receptor

Parathyroid cell calcium-sensing receptor

Related Agents

Approval
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-70037 Cinacalcet Agonist 99.97% Yes
HY-70037A Cinacalcet hydrochloride Agonist 99.99% Yes
HY-P1955A Etelcalcetide hydrochloride Activator 99.61% Unkown
HY-17613 Evocalcet Activator 98.39% Unkown
HY-17397 Strontium Ranelate Activator 99.99% Unkown
HY-P1955 Etelcalcetide Activator / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-10007 NPS-2143 Antagonist 99.33% Phase 2
HY-10167A Tecalcet Hydrochloride Modulator 99.66% Phase 2
Pre-clinical Phase
Bioactive Molecules (26)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103314 Gadolinium chloride Agonist ≥99.0% Unkown
HY-10171 NPS-2143 hydrochloride Antagonist 99.80% Unkown
HY-103320A Calhex 231 hydrochloride Inhibitor 99.81% Unkown
HY-11095 NPS 2390 Inhibitor 98.83% Unkown
HY-112171 γ-L-Glutamyl-L-alanine Modulator ≥98.0% Unkown
HY-N0546 Ligustroflavone Antagonist 99.74% Unkown
HY-12557 γ-Glutamylvaline Activator 99.73% Unkown
HY-109106A Upacicalcet sodium ≥98.0% Unkown
HY-122819 Calindol hydrochloride Agonist 99.88% Unkown
HY-15105 SB-423562 Antagonist 99.66% Unkown
HY-50713 Calcium-Sensing Receptor Antagonists I Antagonist 98.95% Unkown
HY-107773 GSK3004774 Agonist 98.11% Unkown
HY-70037AS Cinacalcet-d3 hydrochloride Agonist 97.63% Unkown
HY-109106 Upacicalcet / Unkown
HY-121584 Lycoperodine-1 Agonist 99.82% Unkown
HY-109106B (Rac)-Upacicalcet ≥95.0% Unkown
HY-15106 SB-423557 Antagonist / Unkown
HY-70037S Cinacalcet-D3 Agonist / Unkown
HY-14752 Ronacaleret Antagonist / Unkown
HY-P4376 Gamma-Glu-Abu Agonist / Unkown
HY-15104 Ronacaleret hydrochloride Antagonist / Unkown
HY-117851 AC-265347 Agonist 99.97% Unkown
HY-103320 Calhex 231 Antagonist / Unkown
HY-153258 CaSR antagonist-1 Antagonist / Unkown
HY-14401 Encaleret Antagonist / Unkown
HY-161113 Z8554052021 Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CASR NCBI NCBI:846