2. Gene
  3. COMT - catechol-O-methyltransferase Gene

COMT - catechol-O-methyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100155530 | Gene type: protein coding

About COMT

Primary_assembly 14: 51,385,738-51,403,998 forward strand.Sscrofa11.1:CM000825.5

This gene has 6 transcripts (splice variants), 276 orthologues and 2 paralogues. Broad expression in liver (RPKM 214.9), mixtures (RPKM 14.8) and 8 other tissues.

COMT Products(1)

mRNA Protein Name
NM_001195330.2 NP_001182259.1 catechol O-methyltransferase

COMT Protein Structure

YrrM

YrrM: cl28097 (49 - 225)

  • 0
  • 100
  • 200
  • 270 a.a.
Protein Preferred Names Protein Names

catechol O-methyltransferase

Related Agents

Approval
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17406 Tolcapone Inhibitor 99.91% Yes
HY-14280 Entacapone Inhibitor 99.97% Yes
HY-14896 Opicapone Inhibitor 99.06% Yes
HY-100562 Flopropione Inhibitor 98.57% Unkown
HY-14280R Entacapone (Standard) Inhibitor / Unkown
HY-17406R Tolcapone (Standard) Inhibitor / Unkown
HY-14280A Entacapone sodium salt Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-N0529 Rosmarinic acid Inhibitor 99.70% Phase 4
HY-106405 Nebicapone Inhibitor 99.61% Phase 2
HY-106842 Nitecapone Inhibitor 99.53% Phase 2
Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151388 hMAO-B/MB-COMT-IN-1 Inhibitor 98.04% Unkown
HY-133068 5-Hydroxyferulic acid 99.80% Unkown
HY-17406S1 Tolcapone-d4 Inhibitor 99.13% Unkown
HY-125339 Ro 41-0960 Inhibitor ≥98.0% Unkown
HY-14280S Entacapone-d10 Inhibitor ≥98.0% Unkown
HY-157719 S-Adenosylhomocysteine sulfoxide Inhibitor ≥95.0% Unkown
HY-100642S 3-O-Methyltolcapone-d7 Inhibitor ≥99.0% Unkown
HY-133068A (E)-5-Hydroxyferulic acid / Unkown
HY-100642 3-O-Methyltolcapone Inhibitor / Unkown
HY-17406S Tolcapone-d7 Inhibitor / Unkown
HY-151390 hMAO-B/MB-COMT-IN-2 Inhibitor / Unkown
HY-100642S1 3-O-Methyltolcapone-d4 Inhibitor / Unkown
HY-162760 COMT-IN-1 Inhibitor / Unkown
HY-119224 BIA 3-335 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens COMT NCBI NCBI:1312