1. Gene
  2. FOXO6 - forkhead box O6 Gene

FOXO6 - forkhead box O6 Gene

Homo sapiens
Gene ID: 100132074 | Gene type: protein coding

About FOXO6

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:41,361,434-41,383,590 (from NCBI)

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of dendritic spine development and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FOXO6 Products(1)

mRNA Protein Name
NM_001291281.3 NP_001278210.2 forkhead box protein O6
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23714368 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FOXO6 Protein Structure

Forkhead

Forkhead: Forkhead domain (91 - 173)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 559 a.a.
Protein Preferred Names Protein Names

forkhead box protein O6

Related Diseases

Diseases Alias
Rhabdomyosarcoma 2

Alveolar Rhabdomyosarcoma

Rhabdomyosarcoma, Alveolar

Rhabdomyosarcoma Alveolar

RMS2

Rmsa

Rhabdomyosarcoma 2, Alveolar

Alveolar Childhood Rhabdomyosarcoma

Arms

Rhabdomyosarcoma, Type 2

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus FOXO6 VGNC VGNC:59182
Felis catus FOXO6 VGNC VGNC:107546
Macaca mulatta FOXO6 VGNC VGNC:99955
Rattus norvegicus FOXO6 RGD RGD:1595858
Mus musculus FOXO6 MGD MGI:2676586