Parkinson's Disease

Parkinsonism is characterized by bradykinesia plus at least one of the following: rest tremor, rigidity, or postural instability, and represents a clinical syndrome seen in various neurodegenerative disorders, including Parkinson disease (PD), progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration, dementia with Lewy bodies (DLB), and Parkinson disease dementia (PDD), among others. While bradykinesia is the core feature across these conditions, patients often exhibit additional motor and nonmotor symptoms. The term "extrapyramidal" is outdated and imprecise, as it inaccurately implies involvement outside the pyramidal system, and its use is discouraged in scientific literature and movement disorder journals.

References: