1. Disease Areas
  2. Cancer Respiratory Disease
  3. Lung Cancer Respiratory Cancer
  4. Large Cell Lung Carcinoma

Large Cell Lung Carcinoma

Large cell lung carcinoma is a subtype of non-small cell lung cancer characterized by large, undifferentiated cells lacking specific features of other lung cancer types such as adenocarcinoma or squamous cell carcinoma. It is associated with genes like NME1, involved in metastasis suppression, and pathways including signaling by receptor tyrosine kinases and the breast cancer pathway. The disease is linked to tissues such as lung and endothelial cells, with phenotypic manifestations involving craniofacial abnormalities and cellular changes. Drugs such as temsirolimus and sirolimus have been explored in its treatment, reflecting potential therapeutic targets within mTOR-related signaling.

Large Cell Lung Carcinoma (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-17394
    Cisplatin 15663-27-1 99.84%
    Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy.
    Cisplatin
  • HY-B0015
    Paclitaxel 33069-62-4 99.97%
    Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.
    Paclitaxel