2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK MAPK/ERK Pathway Stem Cell/Wnt Metabolic Enzyme/Protease
  3. EGFR p38 MAPK ERK Phosphatase
  4. CN009543V

CN009543V is an epidermal growth factor receptor (EGFR) agonist. CN009543V enhances tyrosine phosphorylation of EGFR at Tyr1068 and Tyr1173, thereby activating the MAPK/ERK cascade. CN009543V inhibits the activity of PTP-1B in MDA MB468 cells. CN009543V can be used in cancer research.

For research use only. We do not sell to patients.

CN009543V Chemical Structure

CN009543V Chemical Structure

CAS No. : 375826-84-9

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Based on 1 publication(s) in Google Scholar

CN009543V Related Antibodies

Top Publications Citing Use of Products

View All EGFR Isoform Specific Products:

View All Isoforms
EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

View All p38 MAPK Isoform Specific Products:

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

View All ERK Isoform Specific Products:

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ERK ERK1 ERK2 ERK5 ERK8

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Description

CN009543V is an epidermal growth factor receptor (EGFR) agonist. CN009543V enhances tyrosine phosphorylation of EGFR at Tyr1068 and Tyr1173, thereby activating the MAPK/ERK cascade. CN009543V inhibits the activity of PTP-1B in MDA MB468 cells. CN009543V can be used in cancer research[1].

Molecular Weight

340.31

Formula

C12H12N4O6S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(OC)C(CSC1=CC=C([N+]([O-])=O)C2=NON=C21)NC(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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CN009543V Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CN009543V375826-84-9EGFRp38 MAPKERKPhosphataseEpidermal growth factor receptorErbB-1HER1Extracellular signal regulated kinasesAnticancerMDA MB468 cellsEGF-induced cellsInhibitorinhibitorinhibit

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