2. Cell Cycle/DNA Damage Epigenetics Apoptosis
  3. HDAC Apoptosis
  4. Chlamydocin (purity≥70%)

Chlamydocin (purity≥70%), a fungal metabolite, is a highly potent HDAC inhibitor, with an IC50 of 1.3 nM. Chlamydocin (purity≥70%) exhibits potent antiproliferative and anticancer activities. Chlamydocin (purity≥70%) induces apoptosis by activating caspase-3.

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Chlamydocin (purity≥70%)

Chlamydocin (purity≥70%) Chemical Structure

CAS No. : 53342-16-8

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Chlamydocin (purity≥70%) Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

Chlamydocin (purity≥70%), a fungal metabolite, is a highly potent HDAC inhibitor, with an IC50 of 1.3 nM. Chlamydocin (purity≥70%) exhibits potent antiproliferative and anticancer activities. Chlamydocin (purity≥70%) induces apoptosis by activating caspase-3[1].

IC50 & Target[1]

HDAC

1.3 nM (IC50)

In Vitro

Chlamydocin (purity≥70%) is originally isolated from the fungus Diheterospora chlamydosporia. Chlamydocin (purity≥70%) exhibits a broad spectrum of antiproliferative activity toward various cancer cell lines, irrespective of their p53 status. The antiproliferative activity of Chlamydocin (purity≥70%) is accompanied by accumulation of hyperacetylated histones H3 and H4, induction of p21cip1/waf1, and accumulation of cells in G2/M phase of the cell cycle[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chlamydocin (purity≥70%) Related Antibodies
Molecular Weight

526.62

Formula

C28H38N4O6
CAS No.
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Purity & Documentation
References
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Chlamydocin (purity≥70%) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chlamydocin (purity≥70%)53342-16-8HDACApoptosisHistone deacetylasescyclictetrapeptidaccumulationhyperacetylatedhistonesH3H4A2780ovariancancercellsInhibitorinhibitorinhibit

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