2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Betifisolimab

Betifisolimab (MSB-2311) is a humanized monoclonal antibody directed against the immunosuppressive ligand PD-L1. Betifisolimab has the potential for advanced solid tumors and hematological malignancies research.

For research use only. We do not sell to patients.

CAS No. : 2460539-60-8

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Betifisolimab Related Antibodies

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Description

Betifisolimab (MSB-2311) is a humanized monoclonal antibody directed against the immunosuppressive ligand PD-L1. Betifisolimab has the potential for advanced solid tumors and hematological malignancies research[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Chimeric
In Vitro

Betifisolimab (MSB-2311) is a humanized PD-L1 antibody with a unique pH-dependent antigen binding property that enables intra-tumor recycling and potentiates tumor penetration[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Betifisolimab Related Antibodies
Clinical Trial
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
CAS No.
SMILES

[Betifisolimab]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Purity & Documentation
References
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Betifisolimab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Betifisolimab2460539-60-8MSB-2311MSB2311MSB 2311PD-1/PD-L1PD-1/Programmed death-ligand 1anti-cancer activitiesPD-L1humanized monoclonal antibodyadvanced solid tumorshematological malignanciesInhibitorinhibitorinhibit

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