Tyrosine Hydroxylase Antibody (YA5767)

Tyrosine Hydroxylase Antibody (YA5767) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tyrosine Hydroxylase. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

Tyrosine hydroxylase is an enzyme that plays a pivotal role in the biosynthesis of catecholamines, including dopamine, noradrenaline, and adrenaline. It catalyzes the rate-limiting step in this pathway, converting L-tyrosine to L-dihydroxyphenylalanine (L-Dopa) through the use of tetrahydrobiopterin and molecular oxygen. While its primary substrate is tyrosine, tyrosine hydroxylase also exhibits lower specificity and can hydroxylate phenylalanine and tryptophan. This enzymatic activity is essential for the synthesis of neurotransmitters involved in various physiological processes. Moreover, tyrosine hydroxylase has been found to positively regulate the regression of retinal hyaloid vessels during postnatal development, indicating its diverse roles beyond catecholamine biosynthesis.

P07101

Predicted band size: 59 kDa; Observed band size: 59 kDa

Protein A

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human, Mouse, Rat

IHC: 1:500-1:2000; WB: 1:2000-1:10000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200;

WB, IHC-P, ICC/IF, IP, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG