TWIST1 Antibody (YA4293)

Cat. No.: HY-P84596: Data Sheet User Guide for Antibodies
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TWIST1 Antibody (YA4293) is a mouse-derived and non-conjugated IgG1 antibody, targeting to TWIST1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse, rat, rabbit.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
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Documentation

Description	TWIST1 Antibody (YA4293) is a mouse-derived and non-conjugated IgG1 antibody, targeting to TWIST1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse, rat, rabbit.
Background	TWIST1 is a transcriptional regulator that inhibits myogenesis by sequestering E proteins, suppressing trans-activation by MEF2, and blocking MYOD1's DNA-binding through physical interaction. It also represses pro-inflammatory cytokines like TNFA and IL1B, and regulates cranial suture patterning and fusion. As a heterodimer with E proteins, TWIST1 activates transcription, but its gene regulation varies by dimer composition: homodimers induce FGFR2 and POSTN expression, whereas heterodimers suppress FGFR2 and POSTN while inducing THBS1 expression. Heterodimerization is essential for osteoblast differentiation. Additionally, TWIST1 represses the activity of the circadian transcriptional activator NPAS2-BMAL1 heterodimer (By similarity).
Gene ID	7291 [NCBI]
SwissProt ID	Q15672
Synonyms	SCS; ACS3; CRS1; BPES2; BPES3; TWIST; bHLHa38
Molecular Weight	Predicted band size: 21 kDa; Observed band size: 21 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse, Rat, Rabbit
Dilution Ratio	WB: 1/500-1/2000; IHC: 1/100-1/500; IF: 1/50-1/500; FC: 1/200-1/400; ELISA: 1/10000
Application	WB, IHC-P, ICC/IF, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Purified recombinant fragment of human TWIST1 (AA: 9-74) expressed in E. Coli.
Documentation	Data Sheet (235 KB) User Guide for Antibodies (1077 KB)

TWIST1 Antibody (YA4293) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TWIST1 Antibody (YA4293)

Biological Activity

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TWIST1 Antibody (YA4293) Related Classifications

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