SND1/P100 Antibody (YA5092)

SND1/P100 Antibody (YA5092) is a mouse-derived and non-conjugated monoclonal antibody, targeting to TudorSN. It can be applicated for WB, ELISA assays, in the background of human.

SND1/P100 is an endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, it regulates mRNAs involved in G1-to-S phase transition. It also functions as a bridging factor between STAT6 and the basal transcription factor and plays a role in PIM1 regulation of MYB activity. By similarity, it acts as a transcriptional coactivator for STAT5. In microbial infections, SND1/P100 serves as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2) and promotes SARS-CoV-2 RNA synthesis by binding to negative-sense RNA and the viral protein nsp9.

Q7KZF4

Predicted band size: 102 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:500-1:2000; ELISA: 1:10000

WB, ELISA

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant fragment of TudorSN (aa361-485) expressed in E. Coli.