Rad21 Antibody (YA6313)

Rad21 Antibody (YA6313) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rad21. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

RAD21 is a component of the cohesin complex, which mediates sister chromatid cohesion from DNA replication in S phase to chromosome segregation in mitosis, a process critical for accurate chromosome distribution, post-replicative DNA repair, and suppression of aberrant recombination in repetitive regions. The cohesin complex may also contribute to mitotic spindle pole assembly. During interphase, cohesins potentially regulate gene expression by binding to multiple genomic sites (By similarity). It likely modulates RUNX1 gene expression (Probable) and binds to repress the APOB gene promoter. Additionally, RAD21 might play a role in embryonic gut development, possibly via enteric neuron regulation (By similarity), and may promote apoptosis.

O60216

Predicted band size: 72 kDa; Observed band size: 130 kDa

Protein A

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human, Mouse, Rat

IHC: 1:200-1000; WB: 1:1000-5000; ICC/IF: 1:200-1000; ELISA: 1:5000-20000; IP: 1:50-200

WB, IHC-P, ICC/IF, IP, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG