MBP Antibody (YA5613)

MBP Antibody (YA5613) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MBP. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human, mouse, rat.

The classic group of MBP isoforms (isoform 4-isoform 13) stands as the predominant protein constituents alongside PLP in the myelin membrane of the central nervous system (CNS), playing vital roles in both the formation and stabilization of the myelin sheath. Conversely, the non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may be particularly involved in the early stages of brain development, preceding myelination. These isoforms potentially function as components of transcriptional complexes, contributing to intricate cellular processes. Moreover, members of the non-classic group may participate in signaling pathways within T-cells and neural cells. The extensive repertoire of isomers resulting from differential splicing events and optional post-translational modifications adds complexity, with each isomer potentially serving specialized functions. The MBP protein forms homodimers, further contributing to its diverse functional roles.

P02686

Predicted band size: 33 kDa; Observed band size: 33 kDa

Protein G

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat

IHC: 1:200-1000; WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:1000-5000

IHC-P, WB, ICC/IF, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Synthesized peptide derived from human Myelin Basic Protein(MBP) AA range: 150-250