IghA1 Antibody (YA3611)

IghA1 Antibody (YA3611) is a mouse-derived and non-conjugated IgG1 antibody, targeting to IghA1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse, monkey.

IghA1 is the constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors that, upon binding a specific antigen, trigger clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, leading to the elimination of bound antigens. The antigen-binding site is formed by the variable domain of one heavy chain together with that of its associated light chain, giving each immunoglobulin two antigen-binding sites with high affinity for a specific antigen. The variable domains are assembled through V-(D)-J rearrangement and can undergo somatic hypermutations, which, after antigen exposure and selection, enable affinity maturation for a particular antigen. Ig alpha is the major immunoglobulin class in body secretions. by similar: Membrane-bound immunoglobins function as B cell receptors, while secreted forms act as antibodies.

P01876

Predicted band size: 38 kDa; Observed band size: 60 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human, Mouse, Monkey

WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/50-1/250; FC: 1/200-1/400; ELISA: 1/10000

WB, IHC-P, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human IghA1 (AA: 207-353) expressed in E. Coli.