2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies Flow Cytometry Antibodies
  5. EHD1 Antibody (YA1970)

EHD1 Antibody (YA1970)

Cat. No.: HY-P82225
User Guide for Antibodies Technical Support

EHD1 Antibody (YA1970) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1970), targeting EHD1, with a predicted molecular weight of 61 kDa (observed band size: 61 kDa). EHD1 Antibody (YA1970) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
or Bulk Inquiry

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

EHD1 Antibody (YA1970) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1970), targeting EHD1, with a predicted molecular weight of 61 kDa (observed band size: 61 kDa). EHD1 Antibody (YA1970) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.
Background

EHD1 is an ATP- and membrane-binding protein that regulates membrane reorganization/tubulation through ATP hydrolysis. In vitro, it induces vesiculation of endocytic membranes. This protein participates in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Upon nerve growth factor stimulation, EHD1 is recruited to endosomal membranes and indirectly regulates neurite outgrowth (by similar). It also plays a role in myoblast fusion (by similar) and is involved in the unidirectional retrograde dendritic transport of endocytosed BACE1, as well as its efficient sorting to axons, suggesting a function in neuronal APP processing (by similar). During early ciliogenesis, EHD1 contributes to the formation of the ciliary vesicle (CV), potentially by recruiting the SNARE complex component SNAP29 to promote DAV fusion for CV assembly. It recruits transition zone proteins (e.g., CEP290, RPGRIP1L, TMEM67, and B9D2) and IFT20 after DAV reorganization, followed by Rab8-dependent ciliary membrane extension. EHD1 is essential for the loss of CCP110 from the mother centriole, a critical step in basal body maturation during ciliogenesis.
Gene ID
SwissProt ID
Synonyms
EHD1; H PAST; hPAST1; PAST; PAST homolog 1; PAST1; Tilin
Molecular Weight

Predicted band size: 61 kDa; Observed band size: 61 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Cardiovascular
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100
Application

WB, IHC-P, ICC/IF, IP, FC
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human EHD1
Database

Entrez Gene: 10938 Human ; 13660 Mouse ; 293692 Rat

SwissProt: Q9H4M9 Human ; Q9WVK4 Mouse ; Q641Z6 Rat

OMIM: 605888 Human

Documentation
User Guide for Antibodies (1077 KB)

EHD1 Antibody (YA1970) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
EHD1 Antibody (YA1970)
Cat. No.:
HY-P82225
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.