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  5. EB3 Antibody (YA1775)

EB3 Antibody (YA1775)

Cat. No.: HY-P82030
User Guide for Antibodies Technical Support

EB3 Antibody (YA1775) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1775), targeting EB3, with a predicted molecular weight of 32 kDa (observed band size: 32 kDa). EB3 Antibody (YA1775) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

EB3 Antibody (YA1775) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1775), targeting EB3, with a predicted molecular weight of 32 kDa (observed band size: 32 kDa). EB3 Antibody (YA1775) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.
Background

EB3 is a plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. It promotes microtubule growth and may be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Additionally, EB3 acts as a regulator of minus-end microtubule organization by interacting with the AKAP9-PDE4DIP complex to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, a critical step for polarized cell movement. EB3 also promotes the elongation of CAMSAP2-decorated microtubule stretches on the minus-end. by similar: These functions have been reported in multiple studies.
Gene ID
SwissProt ID
Synonyms
EB3; EBF3; MAPRE3; RP/EB Family; RP3
Molecular Weight

Predicted band size: 32 kDa; Observed band size: 32 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Cell Biology
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100
Application

WB, IHC-P, ICC/IF, FC
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human EB3
Database

Entrez Gene: 22924 Human ; 100732 Mouse ; 298848 Rat

SwissProt: Q9UPY8 Human ; Q6PER3 Mouse ; Q5XIT1 Rat

OMIM: 605788 Human

Documentation
User Guide for Antibodies (1077 KB)

EB3 Antibody (YA1775) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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EB3 Antibody (YA1775)
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