DDX4 Antibody (YA1208)

DDX4 Antibody (YA1208) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1208), targeting DDX4. DDX4 Antibody (YA1208) can be used for IHC-P experiment in human background.

DDX4 is an ATP-dependent RNA helicase essential for spermatogenesis. It suppresses transposable elements to maintain germline integrity via the piRNA metabolic pathway, which involves forming complexes with piRNAs and Piwi proteins during meiosis to regulate transposon methylation and silencing. It participates in the secondary piRNA metabolic process, generating piRNAs in fetal male germ cells through a ping-pong amplification cycle. Additionally, DDX4 supports PIWIL2 slicing-triggered piRNA biogenesis by processing cleavage fragments from PIWIL2 into mature piRNAs via its helicase activity. Some functions are inferred from similarity (By similarity).

Q9NQI0

Predicted band size: 79 kDa; Observed band size: 75 kDa

Affinity Purified

Non-conjugated

Unmodified

AB_3103577

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

IHC: 1/100-1/200

IHC-P

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.228.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human DDX4