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  5. Cytokeratin 15 Antibody (YA1493)

Cytokeratin 15 Antibody (YA1493)

Cat. No.: HY-P81748
COA
SDS
User Guide for Antibodies Technical Support

Cytokeratin 15 Antibody (YA1493) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1493), targeting Cytokeratin 15, with a predicted molecular weight of 49 kDa. Cytokeratin 15 Antibody (YA1493) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse background.

For research use only. We do not sell to patients.

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50 μL In-stock
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Cytokeratin 15 Antibody (YA1493) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1493), targeting Cytokeratin 15, with a predicted molecular weight of 49 kDa. Cytokeratin 15 Antibody (YA1493) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse background.
Background

Cytokeratins (CK) are keratin proteins exclusively found in epithelial tissues, classified as type I (acidic) and type II (basic). As the largest subgroup of intermediate filaments, they form the eukaryotic cytoskeleton alongside other filaments, functioning in epithelial integrity maintenance, injury protection, and cellular communication. Expressed in pairs and numbered 1–20 by molecular weight/isoelectric point, they include simple epithelial types (e.g., CK7, CK8, CK18–20) and complex types (e.g., cutaneous CK5/6, CK10, CK14–15). An alternative system categorizes acidic type I (low MW, CK9–20) and basic type II (high MW, CK1–8). Monoclonal antibodies with varying specificity target these proteins. Released during epithelial stress, Cytokeratins are detectable via commercial UBC Rapid assays (ELISA/point-of-care), showing 59.3% sensitivity and 86.1% specificity, particularly for primary high-grade tumors. by similar: UBC Rapid is developed by IDL Biotech AB.
Gene ID
SwissProt ID
Synonyms
CK-15; CK15; cytokeratin15; K15; K1C15; K1CO; keratin 15; Keratin-15; keratin-15; beta; KRT15; KRTB; type I cytoskeletal 15
Molecular Weight

Predicted band size: 49 kDa; Observed band size: 45 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
RRID
Research Field

Signal Transduction
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100
Application

WB, IHC-P, ICC/IF, FC
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human Cytokeratin 15
Database

Entrez Gene: 3866 Human ; 16665 Mouse ;

SwissProt: P19012 Human ; Q61414 Mouse ;

OMIM: 148030 Human

Documentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Cytokeratin 15 Antibody (YA1493) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cytokeratin 15 Antibody (YA1493)
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