1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. Cytokeratin 10 Antibody (YA5723)

Cytokeratin 10 Antibody (YA5723)

Cat. No.: HY-P86031
User Guide for Antibodies Technical Support

Cytokeratin 10 Antibody (YA5723) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytokeratin 10. It can be applicated for IHC-P, ICC/IF, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Cytokeratin 10 Antibody (YA5723) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytokeratin 10. It can be applicated for IHC-P, ICC/IF, ELISA assays, in the background of human.

Background

Cytokeratin plays a role in establishing the epidermal barrier in plantar skin (by similar). It is involved in maintaining cell layer development and keratin filament bundles in suprabasal epithelial cells (by similar). In microbial infections, Cytokeratin mediates S.aureus adherence to desquamated nasal epithelial cells via clfB, potentially contributing to nasal colonization. Additionally, it binds S.pneumoniae PsrP, facilitating bacterial adherence to lung cell lines. Reduced KRT10 keratin levels decrease adherence, while overexpression enhances it. This interaction does not require glycosylation of either protein.

Gene ID
SwissProt ID
Synonyms
Keratin, type I cytoskeletal 10; Cytokeratin-10; CK-10; Keratin-10; K10;
Molecular Weight

Predicted band size: 60 kDa; Observed band size: 70 kDa

Purity

affinity chromatography.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

Dilution Ratio

IHC: 1:200-400; ICC/IF: 1:50-200; ELISA: 1:500-5000

Application

IHC-P, ICC/IF, ELISA

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Immunogen

Synthesized peptide derived from human CK10 AA range: 500-584

Documentation

Cytokeratin 10 Antibody (YA5723) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cytokeratin 10 Antibody (YA5723)
Cat. No.:
HY-P86031
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