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  5. Cytochrome C Oxidase subunit Vic Antibody (YA2611)

Cytochrome C Oxidase subunit Vic Antibody (YA2611)

Cat. No.: HY-P82866
User Guide for Antibodies Technical Support

Cytochrome C Oxidase subunit Vic Antibody (YA2611) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2611), targeting Cytochrome C Oxidase subunit Vic, with a predicted molecular weight of 9 kDa (observed band size: 12 kDa). Cytochrome C Oxidase subunit Vic Antibody (YA2611) can be used for WB, IHC-P experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Cytochrome C Oxidase subunit Vic Antibody (YA2611) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2611), targeting Cytochrome C Oxidase subunit Vic, with a predicted molecular weight of 9 kDa (observed band size: 12 kDa). Cytochrome C Oxidase subunit Vic Antibody (YA2611) can be used for WB, IHC-P experiment in human, mouse, rat background.
Background

Cytochrome C Oxidase subunit Vic is a component of cytochrome c oxidase, the terminal enzyme in the mitochondrial electron transport chain that drives oxidative phosphorylation. The respiratory chain comprises three multisubunit complexes—succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), and cytochrome c oxidase (complex IV, CIV)—which collaborate to transfer electrons derived from NADH and succinate to molecular oxygen, generating an electrochemical gradient across the inner membrane to power transmembrane transport and ATP synthase. Cytochrome c oxidase catalyzes the reduction of oxygen to water. Electrons from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to two water molecules using four electrons from cytochrome c in the IMS and four protons from the mitochondrial matrix. by similar: Other respiratory chain complexes (e.g., CII and CIII) participate in electron transfer, but Cytochrome C Oxidase subunit Vic is specific to CIV and directly mediates oxygen reduction.
Gene ID
SwissProt ID
Synonyms
cytochrome c oxidase subunit 6C
Molecular Weight

Predicted band size: 9 kDa; Observed band size: 12 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Cardiovascular
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100
Application

WB, IHC-P
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthetic peptide of human Cytochrome C Oxidase subunit Vic
Database

Entrez Gene: 1345 Human ; 12864 Mouse ; 54322 Rat

SwissProt: P09669 Human ; Q9CPQ1 Mouse ; P11951 Rat

OMIM: 124090 Human

Documentation
User Guide for Antibodies (1077 KB)

Cytochrome C Oxidase subunit Vic Antibody (YA2611) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cytochrome C Oxidase subunit Vic Antibody (YA2611)
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