Cpn10 Antibody (YA2190)

Cat. No.: HY-P82445: Data Sheet COA
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Cpn10 Antibody (YA2190) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2190), targeting Cpn10, with a predicted molecular weight of 11 kDa (observed band size: 11 kDa). Cpn10 Antibody (YA2190) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Cpn10 Antibody (YA2190) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	Cpn10 Antibody (YA2190) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2190), targeting Cpn10, with a predicted molecular weight of 11 kDa (observed band size: 11 kDa). Cpn10 Antibody (YA2190) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.
Background	Cpn10 is a co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, it facilitates the correct folding of imported proteins and may prevent misfolding while promoting the refolding and proper assembly of unfolded polypeptides under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, forming a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by ATP binding and association with two heptameric rings of the co-chaperonin Hsp10. This sequesters the substrate protein within the inner cavity of Hsp60, allowing it to fold undisturbed by other cellular components for a certain period. Synchronous hydrolysis of ATP in all Hsp60 subunits leads to the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.
Gene ID	3336 [NCBI]
SwissProt ID	P61604
Synonyms	HSPE1; 10 kDa heat shock protein; mitochondrial; Hsp10; 10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
Molecular Weight	Predicted band size: 11 kDa; Observed band size: 11 kDa
Purity	Affinity Chromatography
Conjugation	Non-conjugated
Modification	Unmodified
RRID	AB_3104553
Research Field	Signal Transduction
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50
Application	WB, IHC-P, ICC/IF, IP
Appearance	Liquid
Formulation	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human Cpn10
Database	Entrez Gene: 3336 Human ; 15528 Mouse ; 25462 Rat SwissProt: P61604 Human ; Q64433 Mouse ; P26772 Rat OMIM: 600141 Human
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (191 KB) User Guide for Antibodies (1077 KB)

Cpn10 Antibody (YA2190) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cpn10 Antibody (YA2190)

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