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  2. Primary Antibodies
  3. Monoclonal Antibodies Recombinant Antibodies
  4. CLPX Antibody (YA2814)

CLPX Antibody (YA2814) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2814), targeting CLPX, with a predicted molecular weight of 69 kDa (observed band size: 69 kDa). CLPX Antibody (YA2814) can be used for WB, ICC/IF experiment in human, mouse, rat, hamster background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

CLPX Antibody (YA2814) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2814), targeting CLPX, with a predicted molecular weight of 69 kDa (observed band size: 69 kDa). CLPX Antibody (YA2814) can be used for WB, ICC/IF experiment in human, mouse, rat, hamster background.

Background

CLXP is an ATP-dependent chaperone that functions as an unfoldase. As part of the ClpXP protease complex, it recognizes specific protein substrates, unfolds them using energy derived from ATP hydrolysis, and translocates them to the proteolytic subunit (CLPP) of the ClpXP complex for degradation. Due to its chaperone activity, CLXP also facilitates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Additionally, this chaperone regulates mitochondrial transcription factor A (TFAM) activity, contributing to the control of mtDNA nucleoid distribution. by similar: These functions involve protein quality control, cofactor integration, and mitochondrial DNA regulation.

Gene ID
SwissProt ID
Synonyms
ATP-dependent Clp protease ATP-binding subunit clpX-like; mitochondrial; CLPX
Molecular Weight

Predicted band size: 69 kDa; Observed band size: 69 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

RRID
Research Field

-

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat, Hamster

Dilution Ratio

WB: 1/500-1/1000;IF: 1/50-1/200

Application

WB, ICC/IF

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthetic peptide of human CLPX

Database
Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CLPX Antibody (YA2814)
Cat. No.:
HY-P83069
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