CIP4 Antibody (YA2503)

Cat. No.: HY-P82758: Data Sheet User Guide for Antibodies
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CIP4 Antibody (YA2503) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CIP4.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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CIP4 Antibody (YA2503) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
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Description	CIP4 Antibody (YA2503) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CIP4.
Background	CIP4 is a protein involved in multiple cellular processes. It is required for insulin-stimulated translocation of GLUT4 to the plasma membrane (by similarity). The protein coordinates membrane tubulation with actin cytoskeleton reorganization during endocytosis by binding to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine, promoting membrane invagination and tubule formation. Additionally, CIP4 promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP, which activates the Arp2/3 complex; this actin polymerization may facilitate the fission of membrane tubules into endocytic vesicles. It is essential for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells, and may be required for the lysosomal retention of FASLG/FASL.
Gene ID	9322 [NCBI]
SwissProt ID	Q15642
Synonyms	STP; CIP4; HSTP; STOT; TRIP-10
Molecular Weight	Predicted band size: 68 kDa; Observed band size: 80 kDa
Purity	Affinity Purified
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Cell Biology
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1:500-1:1000
Application	WB
Appearance	Liquid
Formulation	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthetic peptide of human Cip4
Database	Entrez Gene: 9322 Human ; 106628 Mouse ; 116717 Rat SwissProt: Q15642 Human ; Q8CJ53 Mouse ; P97531 Rat OMIM: 604504 Human
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

CIP4 Antibody (YA2503) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CIP4 Antibody (YA2503)

CIP4 Antibody (YA2503) Featured Recommendations:

Biological Activity

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CIP4 Antibody (YA2503) Related Classifications

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