CFHR5 Antibody (YA4468)

CFHR5 Antibody (YA4468) is a mouse-derived and non-conjugated IgG2a antibody, targeting to CFHR5. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse.

CFHR5 stands at the forefront of complement regulation, actively participating in the intricate dynamics of this regulatory system. In its dimerized forms, CFHR5 demonstrates a notable affinity for tissue-bound complement fragments, effectively challenging the physiological complement inhibitor CFH. This versatile regulator engages in a head-to-tail homodimeric configuration and forms heterodimers with CFHR1 or CFHR2, underlining its adaptable role in orchestrating complement-related processes. Moreover, CFHR5 exhibits the capacity to bind C3b in vitro, adding an additional layer to its repertoire of interactions and highlighting its intricate involvement in the regulation of complement pathways.

Q9BXR6

Predicted band size: 64.4 kDa; Observed band size: 50 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human, Mouse

WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, IHC-P, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG2a

Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. Coli.