Caldesmon Antibody (YA2332)

Cat. No.: HY-P82587: Data Sheet COA
SDS
User Guide for Antibodies
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Caldesmon Antibody (YA2332) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2332), targeting Caldesmon, with a predicted molecular weight of 93 kDa (observed band size: 70-80 kDa). Caldesmon Antibody (YA2332) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Caldesmon Antibody (YA2332) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
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Description	Caldesmon Antibody (YA2332) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2332), targeting Caldesmon, with a predicted molecular weight of 93 kDa (observed band size: 70-80 kDa). Caldesmon Antibody (YA2332) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.
Background	CALD1 is an actin- and myosin-binding protein implicated in regulating actomyosin interactions in smooth muscle and nonmuscle cells (potentially acting as a bridge between myosin and actin filaments). It stimulates tropomyosin binding to actin, thereby stabilizing actin filament structure. In muscle tissues, CALD1 inhibits actomyosin ATPase activity by binding to F-actin, with this inhibition attenuated by calcium-calmodulin and enhanced by tropomyosin. It interacts with actin, myosin, two tropomyosin molecules, and calmodulin. Additionally, CALD1 plays essential roles in cellular mitosis, receptor capping, and Schwann cell migration during peripheral nerve regeneration (by similar).
Gene ID	800 [NCBI]
SwissProt ID	Q05682
Synonyms	CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
Molecular Weight	Predicted band size: 93 kDa; Observed band size: 70-80 kDa
Purity	Affinity Purified
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Cell Biology
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20
Application	WB, IHC-P, IP
Appearance	Liquid
Formulation	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthetic peptide of human Caldesmon
Database	Entrez Gene: 800 Human ; 109624 Mouse ; 25687 Rat SwissProt: Q05682 Human ; Q62736 Rat OMIM: 114213 Human
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (191 KB) User Guide for Antibodies (1077 KB)

Caldesmon Antibody (YA2332) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Caldesmon Antibody (YA2332)

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Caldesmon Antibody (YA2332) Related Classifications

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