Bax Antibody (YA6207)

Bax Antibody (YA6207) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Bax. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

Bax is a protein that plays a key role in the mitochondrial apoptotic process. Under normal conditions, Bax is largely cytosolic due to constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, preventing toxic accumulation at the mitochondrial outer membrane (MOM). Under stress conditions, Bax undergoes a conformational change and translocates to the mitochondrial membrane, triggering cytochrome c release and subsequent apoptosis. Additionally, Bax promotes the activation of CASP3, thereby inducing apoptosis. by similar: These functions have been consistently demonstrated across multiple studies.

Q07812

Predicted band size: 21 kDa; Observed band size: 21 kDa

Protein A

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal

Rabbit

Human, Mouse, Rat

IHC: 1:2000-1:5000; WB: 1:1000-1:5000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200,

WB, IHC-P, ICC/IF, IP, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG