ATP1B1 Antibody (YA2084)

Cat. No.: HY-P82339: Data Sheet COA
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ATP1B1 Antibody (YA2084) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2084), targeting ATP1B1, with a predicted molecular weight of 35 kDa (observed band size: 40-50 kDa). ATP1B1 Antibody (YA2084) can be used for WB, IHC-P experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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ATP1B1 Antibody (YA2084) Featured Recommendations:

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	ATP1B1 Antibody (YA2084) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2084), targeting ATP1B1, with a predicted molecular weight of 35 kDa (observed band size: 40-50 kDa). ATP1B1 Antibody (YA2084) can be used for WB, IHC-P experiment in human, mouse, rat background.
Background	The ATP1B1 protein serves as the non-catalytic component of the active enzyme that catalyzes the hydrolysis of ATP, facilitating the exchange of Na(+) and K(+) ions across the plasma membrane. Its regulatory role is manifested through the assembly of alpha/beta heterodimers, controlling the number of sodium pumps transported to the plasma membrane. Beyond its involvement in ion transport, ATP1B1 plays a vital role in innate immunity by amplifying virus-triggered induction of interferons (IFNs) and interferon-stimulated genes (ISGs). This immune-modulatory function involves the enhancement of TRAF3 and TRAF6 ubiquitination, as well as TAK1 and TBK1 phosphorylation. Additionally, ATP1B1 is implicated in cell adhesion and the establishment of epithelial cell polarity, underscoring its multifaceted contributions to cellular processes beyond ion homeostasis.
Gene ID	481 [NCBI]
SwissProt ID	P05026
Synonyms	Adenosinetriphosphatase; ATP1B; ATP1B1; Atpb 1; ATPBS
Molecular Weight	Predicted band size: 35 kDa; Observed band size: 40-50 kDa
Purity	Affinity Purified
Conjugation	Non-conjugated
Modification	Unmodified
RRID	AB_3104448
Research Field	Signal Transduction
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100
Application	WB, IHC-P
Appearance	Liquid
Formulation	Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human ATP1B1
Database	Entrez Gene: 481 Human ; 11931 Mouse ; 25650 Rat SwissProt: P05026 Human ; P14094 Mouse ; P07340 Rat OMIM: 182330 Human
Documentation	Select Batch: Data Sheet (235 KB) SDS (251 KB) COA (191 KB) User Guide for Antibodies (1077 KB)

ATP1B1 Antibody (YA2084) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ATP1B1 Antibody (YA2084)

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