ASGR2 Antibody (YA3684)

ASGR2 Antibody (YA3684) is a mouse-derived and non-conjugated IgG1 antibody, targeting to ASGR2. It can be applicated for IHC-P, FC, ELISA assays, in the background of human.

ASGR2 Protein plays a pivotal role in cellular processes by mediating the endocytosis of plasma glycoproteins from which the terminal sialic acid residue on complex carbohydrate moieties has been removed. Recognizing terminal galactose and N-acetylgalactosamine units, the receptor facilitates the internalization of ligands, forming a complex that is subsequently transported to a sorting organelle. Within this organelle, the receptor and ligand disassociate, and ASGR2 is recycled back to the cell membrane surface. The protein's engagement in these dynamic processes highlights its significance in the cellular handling of glycoproteins and contributes to the regulation of cellular homeostasis. Notably, ASGR2 also interacts with LASS2, broadening its molecular associations and suggesting potential roles in cellular signaling or coordination.

P07307

Predicted band size: 35 kDa; Observed band size: 35 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human

IHC: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

IHC-P, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human ASGR2 (AA: 80-311) expressed in E. Coli.