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  4. Adiponectin Antibody (YA639)

Adiponectin Antibody (YA639)

Cat. No.: HY-P80004
COA User Guide for Antibodies Technical Support

Adiponectin Antibody (YA639) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Adiponectin.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Adiponectin Antibody (YA639) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Adiponectin.

Background

Adiponectin is a key adipokine that regulates fat metabolism and insulin sensitivity, exhibiting direct anti-diabetic, anti-atherogenic and anti-inflammatory properties. It stimulates AMPK phosphorylation in the liver and skeletal muscle to enhance glucose utilization and fatty-acid oxidation. This protein also antagonizes TNF-alpha by suppressing its expression in tissues like liver and macrophages while counteracting its biological effects. Moreover, Adiponectin inhibits endothelial NF-kappa-B signaling via a cAMP-dependent pathway. Depending on its complex forms (LMW, MMW or HMW), Adiponectin may bind and sequester various growth factors with distinct affinities, thereby modulating cell growth, angiogenesis and tissue remodeling.

Tag

Free

Gene ID
SwissProt ID
Synonyms
30 kDa adipocyte complement related protein; ACDC; ACRP 30; ACRP30; ADIPO_HUMAN; Adipocyte; AdipoQ; Adipose most abundant gene transcript 1; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM 1; apM-1; ApM1; C1q and collagen domain-containing protein; GBP 28; GBP28; Gelatin binding protein; Gelatin binding protein 28; Gelatin-binding protein.
Molecular Weight

Predicted band size: 27 kDa; Observed band size: 30 kDa

Purity

Protein A affinity purified.

Subcellular Location

Secreted.

Conjugation

Non-conjugated

Modification

Unmodified

RRID
Research Field

Signal Transduction

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Mouse

Dilution Ratio

WB: 1:500 ;ICC: 1:50 ;IHC-P: 1:400

Application

WB, ICC/IF, IHC-P

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Mouse Adiponectin.AA range:1-247.

Database

Entrez Gene: 22589 Mouse

SwissProt: Q60994 Mouse

Documentation

Adiponectin Antibody (YA639) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Adiponectin Antibody (YA639)
Cat. No.:
HY-P80004
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