ADAMTS1 Antibody (YA4559)

ADAMTS1 Antibody (YA4559) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ADAMTS1.

ADAMTS1 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1) is a multifunctional protein with diverse roles. It functions as a cartilage proteoglycan cleaver, specifically targeting aggrecan at the '1691-Glu-|-Leu-1692' site within the chondroitin sulfate attachment domain, implicating its involvement in the turnover of cartilage matrix. In addition to its role in musculoskeletal processes, ADAMTS1 exhibits angiogenic inhibitor activity, suggesting a potential function in regulating blood vessel formation. As an active metalloprotease, it may contribute to inflammatory processes and play a role in the development of cancer cachexia. Furthermore, ADAMTS1 is suggested to be critical in follicular rupture, emphasizing its diverse functions in physiological and pathological contexts (

Q9UHI8

Predicted band size: 105 kDa; Observed band size: 70-90 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal Antibody

Mouse

Human

WB: 1:500-1:2000; FC: 1:200-1:400; ELISA: 1:10000

WB, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human ADAMTS1 (AA: 858-960) expressed in E. Coli.