2. Adjuvant
  3. Nucleic Acid Adjuvant
  4. Double-stranded DNAs

Double-stranded DNAs

Double-stranded DNAs (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-160225
    ISD sodium 98.02%
    ISD (interferon stimulatory DNA) sodium is a non-CpG oligomer from the Listeria monocytogenes genome. When transfected into cells, ISD sodium strongly enhances the expression of IFN-β. This ISD-induced response is mediated by the STING-TBK1-IRF3 signaling axis.
    ISD sodium
  • HY-160222
    HSV-60mer sodium
    HSV-60mer sodium is a 60 bp double-stranded oligonucleotide containing viral DNA motifs that derive from the herpes simplex virus 1 (HSV-1) genome. Transfected HSV-60 has been shown to potently induce IFN-β in a Toll-like receptor (TLR)-, DNA-dependent activator of IRFs (DAI)-, and RNA polymerase III (Pol III)-independent, but STING-, TBK1- and IFN regulatory factor 3 (IRF3)-dependent manner.
    HSV-60mer sodium
  • HY-160224
    dsVACV-70mer sodium
    dsVACV-70mer (sodium) is a 70 bp double-stranded oligonucleotide containing viral DNA motifs derived from vaccinia virus DNA. dsVACV-70mer (sodium) has potently induces IFN-β via a STING-dependent manner.
    dsVACV-70mer sodium