2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. ABL1 T315I Recombinant Human Active Protein Kinase

ABL1 T315I Recombinant Human Active Protein Kinase 

Cat. No.: HY-E70640
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The emergence of mutations in the BCR::ABL1 kinase domain (KD) impairs Imatinib Mesylate (HY-50946) binding capacity, thus contributing to Imatinib Mesylate resistance. Identification of these mutations is important for treatment decisions and precision medicine in chronic myeloid leukaemia (CML). ABL1 T315I Recombinant Human Active Protein Kinase is a recombinant ABL1 T315I protein that can be used to study ABL1 T315I-related functions.

For research use only. We do not sell to patients.

ABL1 T315I Recombinant Human Active Protein Kinase

ABL1 T315I Recombinant Human Active Protein Kinase Chemical Structure

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ABL1 T315I Recombinant Human Active Protein Kinase Related Antibodies

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Description

The emergence of mutations in the BCR::ABL1 kinase domain (KD) impairs Imatinib Mesylate (HY-50946) binding capacity, thus contributing to Imatinib Mesylate resistance. Identification of these mutations is important for treatment decisions and precision medicine in chronic myeloid leukaemia (CML). ABL1 T315I Recombinant Human Active Protein Kinase is a recombinant ABL1 T315I protein that can be used to study ABL1 T315I-related functions[1].

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[ABL1 T315I Recombinant Human Active Protein Kinase]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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ABL1 T315I Recombinant Human Active Protein Kinase Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ABL1 T315I Recombinant Human Active Protein KinaseBcr-AblInhibitorinhibitorinhibit

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