2. Signaling Pathways
  3. Anti-infection
  4. Urease
  5. Urease Inhibitor

Urease Inhibitor

Urease Inhibitors (13):

Cat. No. Product Name Effect Purity
  • HY-100956
    Flurofamide
    		Inhibitor
    Flurofamide is an effective bacterial urease inhibitor and antibacterial agent. Flurofamide inhibits urease and partially inhibits the chemotactic activity of Helicobacter pylori strain CPY3401. Flurofamide inhibits the growth of Ureaplasma urealyticum. Flurofamide reduces blood ammonia. Flurofamide can be used in the research of infectious urinary stones.
  • HY-107199
    N-Butylthiophosphoric triamide
    		Inhibitor 99.76%
    N-Butylthiophosphoric triamide (NBPT) is a potent urease inhibitor. Butylthiophosphoric triamide inhibits nitrification and reduces the conversion of urea to NH3 gas.
  • HY-W090317
    2,5-Dimethyl-1,4-benzoquinone
    		Inhibitor 99.35%
    2,5-Dimethyl-1,4-benzoquinone is a jack bean urease (HY-P2767) inhibitor (IC50: 0.98 μM). 2,5-Dimethyl-1,4-benzoquinone can be used in the study of soil urease activity in agriculture.
  • HY-W000932
    Butylboronic acid
    		Inhibitor 99.89%
    Butylboronic acid is a competitive soybean urease inhibitor with an IC50 of 2.9 mM and a Ki of 1.5 mM.
  • HY-147787
    Urease-IN-3
    		Inhibitor
    Urease-IN-3 (Compound L12) is a potent inhibitor of Urease with an IC50 of 1.449 μM. Urease-IN-3 is a flavonoid analogue compound.
  • HY-W278232
    Urease-IN-6
    		Inhibitor 98.89%
    Urease-IN-6 is a potent inhibitor of Urease with an IC50 of 14.2 μM. Urease-IN-6 can be used in study peptic and gastric ulcers .
  • HY-115939
    Urease-IN-2
    		Inhibitor
    Urease-IN-2 (compound 8g) is a non-competitive urease inhibitor with an IC50 of 0.94 μM and a Ki of 1.6 μM. Urease-IN-2 inhibits the Jack bean urease (JBU) in a non-competitive manner.
  • HY-W357738
    Urease-IN-14
    		Inhibitor
    Urease-IN-14 (compound 15) is an urease inhibitor and antioxidant. Urease-IN-14 shows DPPH radical scavenging and urease inhibitory activities with IC50 values 151.7 μM and 41.6 μM, respectively.
  • HY-175169
    Urease-IN-21
    		Inhibitor
    Urease-IN-21 (Compound 11b) is a Urease inhibitor with an IC50 of 0.12  μM. Urease-IN-21 has potent antibacterial activity against helicobacter pylori (H. pylori) and inhibitor activity against P450 enzyme (CYP2C19, CYP2C9, and CYP3A4). Urease-IN-21 can be used for H. pylori infection research.
  • HY-168434
    Urease-IN-19
    		Inhibitor
    Urease-IN-19 (Compound 3c) is a potent urease inhibitor with an IC50 value of 2.7 µM. Urease-IN-19 is promising for research of kidney stones and stomach ulcers.
  • HY-161998
    Urease-IN-16
    		Inhibitor
    Urease-IN-16 (compound 4e) is a urease inhibitor, with an IC50 value of 132 μmol/L. Urease-IN-16 can coordinate with the nickel atom through the oxygen atoms of carbonyl or boronic acid groups. Urease-IN-16 shows great potential as an additive in the development of efficient fertilizers and medical applications.
  • HY-175644
    Urease-IN-22
    		Inhibitor
    Urease-IN-22 (Compound 9L) is a Urease inhibitor with an IC50 of 0.15  μM. Urease-IN-22 is a piperazine-based derivative of Benzimidazole (HY-Y1825).
  • HY-149775
    Urease-IN-10
    		Inhibitor
    Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner.