2. Signaling Pathways
  3. Immunology/Inflammation
    Metabolic Enzyme/Protease
    NF-κB
  4. Reactive Oxygen Species
  5. Reactive Oxygen Species Antagonist

Reactive Oxygen Species Antagonist

Reactive Oxygen Species Antagonists (2):

Cat. No. Product Name Effect Purity
  • HY-162276
    Anticancer agent 188
    		Antagonist 99.10%
    Anticancer agent 188 (compound D43) inhibits DNA synthesis in TNBC cells, leading to cell cycle arrest at the G2/M phase. Anticancer agent 188 has anti-cancer viability by inducing ROS-mediated apoptosis and DNA damage.
  • HY-172876
    FLY26
    		Antagonist
    FLY26 is a selective partial GluN2B antagonist with an IC50 value of 0.64 μM. FLY26 partially inhibits the GluN2B subunit of NMDA receptors, reduces calcium ion influx and reactive oxygen species (ROS) production and activates the BDNF/TrkB/CREB neuroprotective signaling pathway to alleviate neuronal excitotoxicity and mitochondrial dysfunction. FLY26 is promising for research of neurological deficits caused by cerebral ischemia-reperfusion injury.