2. Signaling Pathways
  3. GPCR/G Protein
  4. PACAP Receptor
  5. PACAP Receptor Agonist

PACAP Receptor Agonist

PACAP Receptor Isoform Comparison

PACAP Receptor Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-P3483
    Maxadilan
    		Agonist
    Maxadilan is a specific irreversible PAC1 receptor agonist and a potent vasodilator peptide present in the salivary glands of sand flies. Maxadilan exhibits anti-apoptotic activity in hADSCs. Maxadilan inhibits pro-inflammatory cytokines (TNF-α) and enhances anti-inflammatory mediators (IL-10). Maxadilan can activate leukocytes and inhibit vascular permeability through PAC1 receptors. Maxadilan promotes neural differentiation of human adipose-derived stem cells. Maxadilan can be used to study endotoxin shock, atherosclerosis, and neurodegenerative diseases[1][2][3][4][5].
  • HY-P10768
    Ro 25-1553
    		Agonist
    Ro 25-1553 is a 31 amino acid vasoactive intestinal peptide (VIP) analog, that acts as an agonist for VIP2 receptor (VPAC2 receptor). Ro 25-1553 exhibits a bronchodilator effect in nerve-induced or Carbachol (HY-B1208)-induced tracheal smooth muscle contraction in guinea pig model.