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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9899):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W010543S
    N-Isopropylacrylamide-d7
    N-Isopropylacrylamide-d7 is the deuterium labeled N-Isopropylacrylamide.
    N-Isopropylacrylamide-d<sub>7</sub>
  • HY-145603S
    Vanzacaftor-d4
    Vanzacaftor-d4 (VX-121-d4) is the deuterium labeled Vanzacaftor (HY-145603). Vanzacaftor is an orally active noval corrector of Cystic fibrosis transmembrane conductance regulator (CFTR). Vanzacaftor improves processing and trafficking of CFTR protein as well as increases chloride transport in triple combined with Tezacaftor (HY-15448) and Deutivacaftor. Vanzacaftor-Tezacaftor-Deutivacaftor is safe and well tolerated, improving lung function, respiratory symptoms, and CFTR function with cystic fibrosis, which is promising for research in the field of cystic fibrosis diseases.
    Vanzacaftor-d<sub>4</sub>
  • HY-108226S
    Regorafenib N-oxide and N-desmethyl (M5)-d3
    Regorafenib N-oxide and N-desmethyl (M5)-d3 is deuterium labeled Regorafenib N-oxide and N-desmethyl (M5).
    Regorafenib N-oxide and N-desmethyl (M5)-d<sub>3</sub>
  • HY-W744599
    Desoxymetasone-d5
    Desoxymetasone-d5 is the deuterium labeled Desoxymetasone-d5 (HY-W744599).
    Desoxymetasone-d<sub>5</sub>
  • HY-165688S
    Alternariol-9-monomethylether-3-glucoside-d3
    Alternariol-9-monomethylether-3-glucoside-d3 is deuterium labeled Alternariol-9-monomethylether-3-glucoside.
    Alternariol-9-monomethylether-3-glucoside-d<sub>3</sub>
  • HY-118830S
    13,14-Dihydro-15-keto prostaglandin D2-d4
    13,14-Dihydro-15-keto prostaglandin D2-d4 (DK-PGD2-d4) is deuterium labeled 13,14-Dihydro-15-keto prostaglandin D2. 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation.
    13,14-Dihydro-15-keto prostaglandin D2-d<sub>4</sub>
  • HY-W127532S
    cis-4-Hepten-1-ol-d2
    cis-4-Hepten-1-ol-d2 is deuterated labeled cis-4-Hepten-1-ol (HY-W127532). cis-4-Hepten-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    cis-4-Hepten-1-ol-d<sub>2</sub>
  • HY-W654214
    4-Hydroxy nonenal mercapturic acid-d3
    4-Hydroxy nonenal mercapturic acid-d3 is the deuterium labeled 4-Hydroxy nonenal mercapturic acid-d3 (HY-W654214).
    4-Hydroxy nonenal mercapturic acid-d<sub>3</sub>
  • HY-B0161S
    Duloxetine-d7
    Duloxetine-d7 ((S)-Duloxetine-d7) is the deuterium labeled Duloxetine. Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
    Duloxetine-d<sub>7</sub>
  • HY-14199S
    Selegiline-d5 hydrochloride
    Selegiline-d5 (hydrochloride) (Deprenyl-d5 (hydrochloride)) is deuterium labeled Selegiline (hydrochloride). Selegiline (Deprenyl) hydrochloride is a potent, selective and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. Selegiline hydrochloride exhibits 450-flod selectivity for MAO-B over MAO-A (IC50=23 μM). Selegiline hydrochloride can be used for the research of Parkinson's disease, Alzheimer's disease and major depressive disorder.
    Selegiline-d<sub>5</sub> hydrochloride
  • HY-15463S3
    Imatinib-13C,d3
    Imatinib-13C,d3 (STI571-13C,d3) is 13C labeled Imatinib. Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV.
    Imatinib-<sup>13</sup>C,d<sub>3</sub>
  • HY-12366S
    Ubrogepant-d5
    Ubrogepant-d5 (MK-1602-d5) is deuterium labeled Ubrogepant. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine.
    Ubrogepant-d<sub>5</sub>
  • HY-W653942
    Docetaxel-d5
    Docetaxel-d5 is deuterium-labeled Docetaxel (HY-B0011).
    Docetaxel-d<sub>5</sub>
  • HY-W716411S
    1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene-13C12
    1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene-13C12 is 13C labeled 1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene.
    1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene-<sup>13</sup>C<sub>12</sub>
  • HY-167583S
    17:0-20:3 PI-d5
    17:0-20:3 PI-d5 (1-heptadecanoyl-2-eicosatrienoyl-sn-glycero(d5)-3-phosphoinositol (ammonium)) is deuterium labeled 17:0-20:3 PI.
    17:0-20:3 PI-d<sub>5</sub>
  • HY-15851S1
    Revefenacin-d9
    Revefenacin-d9 (TD-4208-d9) is deuterium labeled Revefenacin. Revefenacin (TD-4208; GSK1160724) is a potent mAChR antagonist; has a high affinity on M3 receptor with a Ki of 0.18 nM.
    Revefenacin-d<sub>9</sub>
  • HY-W654082
    Bisphenol e-13C6
    Bisphenol e-13C6 is 13C labeled Bisphenol E. Bisphenol E (4,4'-Ethylidenediphenol) is a biochemical reagent.
    Bisphenol e-<sup>13</sup>C<sub>6</sub>
  • HY-10284S5
    Linagliptin-d6
    Linagliptin-d6 (BI 1356-d6) is deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
    Linagliptin-d<sub>6</sub>
  • HY-165699S
    Methanone, 1,1′-[1,4-butanediylbis[oxy(2-hydroxy-4,1-phenylene)]]bis[phenyl-d10
    Methanone, 1,1′-[1,4-butanediylbis[oxy(2-hydroxy-4,1-phenylene)]]bis[phenyl-d10 is deuterium labeled Methanone, 1,1′-[1,4-butanediylbis[oxy(2-hydroxy-4,1-phenylene)]]bis[phenyl.
    Methanone, 1,1′-[1,4-butanediylbis[oxy(2-hydroxy-4,1-phenylene)]]bis[phenyl-d<sub>10</sub>
  • HY-116666S
    (Rac)-Etomidate acid-d5
    (Rac)-Etomidate acid-d5 is the deuterium labeled (Rac)-Etomidate acid.
    (Rac)-Etomidate acid-d<sub>5</sub>