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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9898):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1418S2
    Tazobactam-15N,d2
    Tazobactam-15N,d2 (CL-298741-15N,d2) is 15N and deuterium labeled Tazobactam. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research.
    Tazobactam-<sup>15</sup>N<sub>,d<sub>2</sub>
  • HY-B0451AS6
    Dopamine-13C,15N hydrochloride
    99.02%
    Dopamine-13C,15N (hydrochloride) is the 13C and 15N labeled Dopamine hydrochloride.
    Dopamine-<sup>13</sup>C,<sup>15</sup>N hydrochloride
  • HY-165704S
    2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4
    2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4 is deuterium labeled 2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium).
    2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d<sub>4</sub>
  • HY-W778555
    Diclofenamide-13C6
    Diclofenamide-13C6 is 13C-labeled Diclofenamide (HY-B0397).
    Diclofenamide-13C6
  • HY-B0168S
    Milnacipran-d10 hydrochloride
    Milnacipran-d10 (hydrochloride) is the deuterium labeled Milnacipran hydrochloride (HY-B0168A). Milnacipran hydrochloride is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran hydrochloride inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (Ki values of 31 and 8.5 nM, respectively). Milnacipran hydrochloride inhibits pERK1/2 activation. Milnacipran hydrochloride has antidepressant, anxiolytic and analgesic properties. Milnacipran hydrochloride inhibits biting behavior in mice. Milnacipran hydrochloride can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia).
    Milnacipran-d<sub>10</sub> hydrochloride
  • HY-W653978
    Cinacalcet-d4 hydrochloride
    Cinacalcet-d4 (AMG-073-d4) hydrochlorideis deuterium labeled Cinacalcet (hydrochloride). Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
    Cinacalcet-d<sub>4</sub> hydrochloride
  • HY-B0511S3
    Biotin-13C5
    Biotin-13C5 (Vitamin B7-13C5) is 13C labeled Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
    Biotin-<sup>13</sup>C<sub>5</sub>
  • HY-78841S
    (2S,4S)-Sacubitril-d4
    (2S,4S)-Sacubitril-d4 is deuterium labeled (2S,4S)-Sacubitril. (2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is a potent NEP inhibitor that can be used for the research of heart failure.
    (2S,4S)-Sacubitril-d<sub>4</sub>
  • HY-W101602S
    2-Isobutyl-3-methylpyrazine-dsub>3
    2-Isobutyl-3-methylpyrazine-d3 is deuterated labeled 2-Isobutyl-3-methylpyrazine.
    2-Isobutyl-3-methylpyrazine-dsub>3</sub>
  • HY-B0072S
    Tropisetron-d5
    Tropisetron-d5 (SDZ-ICS-930-d5 (free base)) is deuterium labeled Tropisetron. Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT3R antagonists with a Ki of 5.3 nM. Tropisetron is also a partial agonist of α7 nicotinic receptor (α7 nAChR) with an EC50 of 1.3 μM. In addition, Tropisetron has antitumor and neuroprotective effects.
    Tropisetron-d<sub>5</sub>
  • HY-112251S
    D-Lin-MC3-DMA-13C3
    D-Lin-MC3-DMA-13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
    D-Lin-MC3-DMA-<sup>13</sup>C<sub>3</sub>
  • HY-B0281AS
    Ranitidine-d6 hydrochloride
    Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride (HY-B0281A). Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine hydrochloride antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride inhibits breast tumor development and spread in mice.
    Ranitidine-d<sub>6</sub> hydrochloride
  • HY-107608S1
    Leukotriene B4-d5
    Leukotriene B4-d5 (LTB4-d5) is deuterium labeled Leukotriene B4. Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    Leukotriene B4-d<sub>5</sub>
  • HY-W012507S1
    2,6-Dichlorobenzoic acid-13C6
    2,6-Dichlorobenzoic acid-13C6 is 13C labeled 2,6-Dichlorobenzoic acid.
    2,6-Dichlorobenzoic acid-<sup>13</sup>C<sub>6</sub>
  • HY-B1966S
    Diphenyl phthalate-3,4,5,6-d4
    Diphenyl phthalate-3,4,5,6-d4 is the deuterium labeled Diphenyl phthalate.
    Diphenyl phthalate-3,4,5,6-d<sub>4</sub>
  • HY-W013049S2
    Docosanoic acid-d2
    Docosanoic acid-d2 (Behenic acid-d2) is deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
    Docosanoic acid-d<sub>2</sub>
  • HY-N9600S
    Dotriacontane-d66
    99.09%
    Dotriacontane-d66 is the deuterium labeled Dotriacontane.
    Dotriacontane-d<sub>66</sub>
  • HY-W588193S
    Cortol-d5
    Cortol-d5 is deuterium-labeled Cortol (HY-W588193).
    Cortol-d<sub>5</sub>
  • HY-166898S
    trans Nonachlor-13C10
    trans Nonachlor-13C10 is 13C labeled (1R,2R,3S,3aR,4R,7R,7aS)-1,2,3,4,5,6,7,8,8-Nonachloro-2,3,3a,4,7,7a-hexahydro-1H-4,7-methanoindene.
    trans Nonachlor-<sup>13</sup>C<sub>10</sub>
  • HY-144367S
    N-Acetyl-S-(2-hydroxy-3-propionamide)-L-cysteine-d3 dicyclohexylammonium
    N-Acetyl-S-(2-hydroxy-3-propionamide)-L-cysteine-d3 (dicyclohexylammonium) is the deuterium labeled N-Acetyl-S-(2-hydroxy-3-propionamide)-L-cysteine (dicyclohexylammonium).
    N-Acetyl-S-(2-hydroxy-3-propionamide)-L-cysteine-d<sub>3</sub> dicyclohexylammonium