2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9896):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W101298S
    (Leu-13C6,15N)-Ile-OH TFA
    (Leu-13C6,15N)-Ile-OH (L-Leucyl-13C6,15N-L-isoleucine) TFA is the deuterium labeled Leu-Ile-OH. Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) synthesis.
    (Leu-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N)-Ile-OH TFA
  • HY-W796728S
    1,2-Bis(methylthio)benzene-d6
    1,2-Bis(methylthio)benzene-d6 is the deuterium labeled 1,2-Bis(methylthio)benzene (HY-W654023).
    1,2-Bis(methylthio)benzene-d<sub>6</sub>
  • HY-18767S2
    Ivosidenib-13C5
    Ivosidenib-13C5 (AG-120-13C5) is 13C labeled Ivosidenib. Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.
    Ivosidenib-<sup>13</sup>C<sub>5</sub>
  • HY-113209S2
    8-Isoprostaglandin F2α-13C5
    8-Isoprostaglandin F2α-13C5 is 13C labeled 8-Isoprostaglandin F2α (HY-113209). 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.
    8-Isoprostaglandin F2α-<sup>13</sup>C<sub>5</sub>
  • HY-124901S
    Tetrasul-d4
    Tetrasul-d4 is the deuterium labeled Tetrasul.
    Tetrasul-d<sub>4</sub>
  • HY-126042S
    (±)-Lisofylline-d6
    (±)-Lisofylline-d6 is the deuterium labeled (±)-Lisofylline.
    (±)-Lisofylline-d<sub>6</sub>
  • HY-B0134S1
    Bestatin-d10
    Bestatin-d10 (Ubenimex-d10) is deuterium labeled Bestatin. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects.
    Bestatin-d<sub>10</sub>
  • HY-B0343S
    Sarafloxacin-d8
    Sarafloxacin-d8 is the deuterium labeled Sarafloxacin(HY-B0343).Sarafloxacin (A-56620) is a fluoroquinolone antimicrobial agent.
    Sarafloxacin-d<sub>8</sub>
  • HY-138687S1
    Nirmatrelvir-d6
    Nirmatrelvir-d6 (PF-07321332-d6) is deuterium labeled Nirmatrelvir. Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research.
    Nirmatrelvir-d<sub>6</sub>
  • HY-Y0078S
    Cinnamyl Alcohol-d5
    Cinnamyl Alcohol-d5 is deuterated labeled Cinnamyl Alcohole (HY-Y0045). Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, exhibits anti-obesity, antioxidant and anti-inflammatory activities.
    Cinnamyl Alcohol-d<sub>5</sub>
  • HY-23805S
    3,6-Dichloro-9H-carbazole-13C12
    3,6-Dichloro-9H-carbazole-13C12 is 13C labeled 3,6-Dichloro-9H-carbazole.
    3,6-Dichloro-9H-carbazole-<sup>13</sup>C<sub>12</sub>
  • HY-14447S1
    Bilastine-d4
    Bilastine-d4 is deuterium labeled Bilastine. Bilastine is an oral histamine H1-receptor antagonist. Bilastine can be used for allergic rhinitis and urticaria studies, and it also improves diabetic nephropathy in mice, showing safety for the central nervous system.
    Bilastine-d<sub>4</sub>
  • HY-W013812S1
    Ethyl linoleate-d5
    Ethyl linoleate-d5 (Linoleic Acid ethyl ester-d5) is deuterium labeled Ethyl linoleate. Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators.
    .
    Ethyl linoleate-d<sub>5</sub>
  • HY-N1369S1
    Menthol-d2
    Menthol-d2 is deuterated labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes.
    Menthol-d<sub>2</sub>
  • HY-W052144S
    (±) Anabasine-d4 dihydrochloride
    (±) Anabasine-d4 dihydrochloride is deuterium labeled (±) Anabasine dihydrochloride. (±) Anabasine dihydrochloride is the racemate of Anabasine dihydrochloride. Anabasine dihydrochloride is an agonist of α7nAChR and exhibits anti-inflammatory and insecticidal activities.
    (±) Anabasine-d<sub>4</sub> dihydrochloride
  • HY-W710512
    Propane-1,2,3-triyl tritricosanoate-d5
    Propane-1,2,3-triyl tritricosanoate-d5 (Glycerol Tritricosanoate-d5) is deuterium labeled Propane-1,2,3-triyl tritricosanoate. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
    Propane-1,2,3-triyl tritricosanoate-d<sub>5</sub>
  • HY-116578S
    Metopimazine-d6
    Metopimazine-d6 (EXP999-d6; RP9965-d6) is the deuterium labeled Metopimazine (HY-116578). Metopimazine (EXP999; RP9965) is a phenothiazine, orally available, selective dopamine D2 receptor antagonist that does not penetrate the blood-brain barrier. Metopimazine blocks dopamine D2 receptors in the chemoreceptor trigger zone and the periphery, thereby inhibiting nausea and vomiting. Metopimazine is indicated for chemotherapy-induced nausea and vomiting, and has low central side effects due to its poor brain penetration. The use of metopimazine in acute gastroenteritis may have potential risks.
    Metopimazine-d<sub>6</sub>
  • HY-W777533
    N-Acetyl sulfadiazine-13C6
    N-Acetyl sulfadiazine-13C6 is 13C labeled N-Acetyl sulfadiazine.
    N-Acetyl sulfadiazine-<sup>13</sup>C<sub>6</sub>
  • HY-B0580S1
    Ketorolac-d4
    Ketorolac-d4 (RS37619 D4) is the deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2.
    Ketorolac-d<sub>4</sub>
  • HY-B0185S
    N-Oxide Lidocaine-d10
    N-Oxide Lidocaine-d10 is the deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia.
    N-Oxide Lidocaine-d<sub>10</sub>