Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (3)

Isotope-Labeled Compounds Related Products (9898):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W752886

Estradiol 3-d₃ (β-D-Glucuronide) sodium
Estradiol 3-d₃ (β-D-Glucuronide) sodium is the deuterium labeled Estradiol 3-(β-D-Glucuronide) sodium (HY-N7755). Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies.

HY-W654000

Cyclic GMP-¹³C,¹⁵N₂
Cyclic GMP-¹³C,¹⁵N₂ is ¹³C and ¹⁵N labeled Cyclic GMP (HY-113469). Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses.

HY-B0660S1

Eicosapentaenoic acid 1,2,3,4,5-¹³C₅
Eicosapentaenoic acid 1,2,3,4,5-¹³C₅ (EPA 1,2,3,4,5-¹³C, FA 20:5-¹³C₅) is ¹³C labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation.

HY-W744235

Levofloxacin-d₃ sodium
Levofloxacin-d₃ sodium is the deuterium labeled Levofloxacin sodium (HY-B0330C). Levofloxacin ((-)-Ofloxacin) sodium is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin sodium inhibits the DNA gyrase and topoisomerase IV. Levofloxacin sodium can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin sodium shows anti-orthopoxvirus activity.

HY-W709612

Regorafenib N-oxide and N-desmethyl (M5)-d₃-1
Regorafenib N-oxide and N-desmethyl (M5)-d₃-1 (N-Desmethyl regorafenib N-oxide-d₃-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4.

HY-W010153S

3-(Trifluoromethyl)phenol-d₄
3-(Trifluoromethyl)phenol-d₄ is the deuterium labeled 3-(Trifluoromethyl)phenol.

HY-150531S

Safinamide d₃
Safinamide d₃ is the deuterium labeled Safinamide.

HY-W451242

1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈		98.20%
1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled 1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈.

HY-135336S

(R)-Verapamil-d₇ hydrochloride
(R)-Verapamil-d₇ (hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents.

HY-N1420AS2

Rhamnose-¹³C-2 monohydrate		99.0%
Rhamnose-¹³C-2 (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate

HY-W011222S1

1-Bromooctadecane-18,18,18-d₃
1-Bromooctadecane-18,18,18-d₃ is the deuterium labeled 1-Bromooctadecane.

HY-78571S

3-Methylbenzoic acid-d₇
3-Methylbenzoic acid-d₇ is the deuterium labeled 3-Methylbenzoic acid.

HY-W069504S

n-Propyl-amine-d₇ Hydrochloride
n-Propyl-amine-d₇ (Hydrochloride) is the deuterium labeled Propan-1-amine hydrochloride.

HY-124878S

LY 227942-d₅
LY 227942-d₅ is the deuterium labeled LY 227942.

HY-12650S

Mirogabalin-¹³C₂,d₁ (Mixture of Diastereomers)
Mirogabalin-¹³C₂,d₁ (Mixture of Diastereomers) is a ¹³C and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS.

HY-13609S

Deflazacort-d₅
Deflazacort-d₅ is the deuterium labeled Deflazacort. Deflazacort, a glucocorticoid, is an inactive proagent and is converted rapidly to the active metabolite 21-desacetyldeflazacort. Deflazacort is used as an anti-inflammatory and immunosuppressant.

HY-146635S

(25RS)-26-Hydroxycholesterol-d₄
(25RS)-26-Hydroxycholesterol-d₄ is the deuterium labeled (25RS)-26-Hydroxycholesterol.

HY-W716691

3-(Allyloxy)-4-methoxybenzaldehyde-d₃
3-(Allyloxy)-4-methoxybenzaldehyde-d₃ is the deuterium labeled 3-(Allyloxy)-4-methoxybenzaldehyde (HY-W319978).

HY-B0442S1

Vardenafil-d₄
Vardenafil-d₄ is deuterium-labeled Vardenafil (HY-B0442).

HY-W141928S

N-Isobutyryl-glycine-d₇		99.0%
N-Isobutyryl-glycine-d₇ is the deuterium labeled N-Isobutyryl-glycine.

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