2. Signaling Pathways
  3. Others
  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0824
    CY7-SE
    		≥98.0%
    CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    CY7-SE
  • HY-D0250
    o-Cresolphthalein complexone
    o-Cresolphthalein complexone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    o-Cresolphthalein complexone
  • HY-D2175
    AF 555 NHS ester
    AF 555 NHS ester is a bright, orange-red fluorescence probe. AF 555 NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. AF 555 exhibits average excitation wavelengths under green laser and red laser of 552 nm and 566 nm, respectively.
    AF 555 NHS ester
  • HY-D1251
    TRFS-red
    TRFS-red, a red fluorescence emission off-on probe, is selective for thioredoxin reductase (TrxR). TRFS-red exhibits high response rate and sensitivity. TRFS-red can be used for imaging live cells.
    TRFS-red
  • HY-D1853A
    Sulfo-Cy5 carboxylic acid TEA
    		98.82%
    Sulfo-Cy5 carboxylic acid TEA is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm).
    Sulfo-Cy5 carboxylic acid TEA
  • HY-D1796
    Vari Fluor 594 SE
    Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 594 SE
  • HY-P4920
    Mca-SEVNLDAEFK(Dnp)-NH2
    		98.96%
    Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1.
    Mca-SEVNLDAEFK(Dnp)-NH2
  • HY-D1377
    Citrulline-specific probe-rhodamine hydrate
    Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis.
    Citrulline-specific probe-rhodamine hydrate
  • HY-D1666
    BDP 558/568 azide
    BDP 558/568 azide is an azide modified BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 azide can be used in the labeling of click chemistry. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    BDP 558/568 azide
  • HY-131026
    Janelia Fluor® 635, SE
    		99.30%
    Janelia Fluor® 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 635, SE
  • HY-D1119
    AF647-NHS ester
    		99.74%
    AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light.
    AF647-NHS ester
  • HY-153232
    eGFP circRNA-LNP
    eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry.
    eGFP circRNA-LNP
  • HY-151708
    CalFluor 488 Azide
    CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    CalFluor 488 Azide
  • HY-118924
    IR-825
    		98.27%
    IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal treatment..
    IR-825
  • HY-D2268A
    QM-FN-SO3 ammonium
    QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission.
    QM-FN-SO3 ammonium
  • HY-NP087
    Lens Culinaris Agglutinin
    Lens Culinaris Agglutinin (LCA) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Lens Culinaris Agglutinin (LCA) is a biological material or organic compound that can be used in life science research.
    Lens Culinaris Agglutinin
  • HY-NP163E
    Wheat germ agglutinin-AF647
    Wheat germ agglutinin-AF647 (WGA-AF647) is a plant lectin that contains the fluorescent dye AF647, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF647 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA.
    Wheat germ agglutinin-AF647
  • HY-D0164
    Naphthol AS-BI
    		99.71%
    Naphthol AS-BI is a substrate of β-glucuronidase and produces a bright red effect after staining biological tissues.
    Naphthol AS-BI
  • HY-116070
    Iodoantipyrine
    		≥98.0%
    Iodoantipyrine (4-Iodoantipyrine) is an iodinated Antipyrine (HY-B0171) with potential antiviral activity. Antipyrine (Phenazone) is an antipyretic and analgesic that also serves as a molecular probe of hepatic oxidative metabolites.
    Iodoantipyrine
  • HY-D1274C
    Sulfo-cyanine3 azide potassium
    		98.08%
    Sulfo-cyanine3 azide potassium is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide potassium can be used for synthesis of fused tricyclic heterocycles, producing immunostimulatory agents. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Sulfo-cyanine3 azide potassium
Cat. No. Product Name / Synonyms Application Reactivity