2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-NP163C
    Wheat germ agglutinin-AF555
    Wheat germ agglutinin-AF555 (WGA-AF555) is a plant lectinthat contains the fluorescent dye AF555, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF555 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA.
    Wheat germ agglutinin-AF555
  • HY-D1342
    Coumberol
    		99.99%
    Coumberol is a fluorescent substrate of AKR1C3 protein. Coumberol can be used for the research of AKR1C3.
    Coumberol
  • HY-W800809
    FAM DBCO, 6-isomer
    FAM DBCO, 6-isomer represents a variant of a time-honored fluorescent dye and featuring a terminal DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy.
    FAM DBCO, 6-isomer
  • HY-D0808
    Meldola blue
    Meldola blue is a biosensor for measuring lactate in serum based on screen-printed carbon electrodes modified with Meldola's Blue-Reinecke salt (MBRS-SPCE) coated with lactate dehydrogenase NAD+-dependent enzyme (from pig heart) and NAD+.
    Meldola blue
  • HY-W027773
    7-Methoxy-4-(trifluoromethyl)coumarin
    		98.0%
    7-Methoxy-4-(trifluoromethyl)coumarin (MFC) is a fluorescent substrate for cytochrome P450 and can quantify CYP activity.
    7-Methoxy-4-(trifluoromethyl)coumarin
  • HY-P10174A
    ADAM-17 Substrate TFA
    		98.00%
    ADAM-17 Substrate is a fluorescent substrate of ADAM.
    ADAM-17 Substrate TFA
  • HY-D1482
    Sulfo-Cy5-tetrazine
    Sulfo Cy5-tetrazine is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Sulfo-Cy5-tetrazine
  • HY-D1044
    Rhodamine 101 chloride
    Rhodamine 101 chloride (Rhodamine 640 chloride) is a fluorescent dye with excitation and emission maxima at 565 nM and 595 nM, respectively. Rhodamine 101 chloride binds to intracellular proteins and emits specific fluorescence. Rhodamine 101 chloride can be used in colon cancer research.
    Rhodamine 101 chloride
  • HY-N0938
    Safflower yellow
    Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius) and as the traditional Chinese medicine it has been extensively used for the treatment of cardio cerebrovascular diseases.
    Safflower yellow
  • HY-P1004A
    Luciferase, firefly
    		98.0%
    Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles.
    Luciferase, firefly
  • HY-D1046
    Dabcyl acid, SE
    		99.61%
    Dabcyl acid, SE is the amino-reactive form of Dabcyl acid (DABCYL), and widely used to prepare a variety of FRET-based probes that contain DABCYL.
    Dabcyl acid, SE
  • HY-P2467
    Biotin-TAT (47-57)
    		98.56%
    Biotin-TAT (47-57), a biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used protein transduction domains (PTDs) into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis.
    Biotin-TAT (47-57)
  • HY-N0573S
    Umbelliferone-d5
    		≥98.0%
    Umbelliferone-d5 (7-Hydroxycoumarin-d5) is the deuterium labeled Umbelliferone (HY-N0573 ). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats.
    Umbelliferone-d<sub>5</sub>
  • HY-D1029A
    Biotin-11-dUTP trisodium
    		≥99.0%
    Biotin-11-dUTP trisodium is a fluorescent substitute for dTTP.
    Biotin-11-dUTP trisodium
  • HY-P4426A
    Lys-Pro-AMC diTFA
    Lys-Pro-AMC diTFA is a fluorogenic substrate for the detection and measurement of the activity of specific enzymes.
    Lys-Pro-AMC diTFA
  • HY-D1570
    BODIPY FL C12
    		99.79%
    BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 480/508 nm.
    BODIPY FL C12
  • HY-W035138
    Tetra(p-bromophenyl)porphyrin
    Tetra(p-bromophenyl)porphyrin (compound 5c) is a fluorescent dye. Tetra(p-bromophenyl)porphyrin can be used for the synthesis of perfuoroalkyl-substituted tetrakisphenylporphyrins.
    Tetra(p-bromophenyl)porphyrin
  • HY-NP079
    Ricinus Communis Agglutinin I
    Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research.
    Ricinus Communis Agglutinin I
  • HY-N0573R
    Umbelliferone (Standard)
    Umbelliferone (Standard) (7-Hydroxycoumarin (Standard)) is the analytical standard of Umbelliferone (HY-N0573). This product is intended for research and analytical applications. Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats.
    Umbelliferone (Standard)
  • HY-D1693
    FBBBE
    		99.0%
    FBBBE is used to detect the production of H2O2 by cells. FBBBE can be triggered by intracellular H2O2 and converted to fluorescein, resulting in an increase in intracellular fluorescence (Ex=4480 nm, Em=512 nm).
    FBBBE
Cat. No. Product Name / Synonyms Application Reactivity