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  3. WX-02-23

WX-02-23 is a tryptoline acrylamide stereoprobe. WX-02-23 blocks CJR-6A reactivity with MBP-FOXA1-FKHD protein with an IC50 of 8 µM.

For research use only. We do not sell to patients.

WX-02-23 Chemical Structure

WX-02-23 Chemical Structure

CAS No. : 2929223-35-6

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Based on 1 publication(s) in Google Scholar

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Description

WX-02-23 is a tryptoline acrylamide stereoprobe. WX-02-23 blocks CJR-6A reactivity with MBP-FOXA1-FKHD protein with an IC50 of 8 µM[1].

Molecular Weight

459.49

Formula

C26H25N3O5

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C=C)N([C@H](C(N1CCOCC1)=O)C2)[C@H](C3=CC=C(OCO4)C4=C3)C5=C2C6=C(N5)C=CC=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (108.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1763 mL 10.8816 mL 21.7633 mL
5 mM 0.4353 mL 2.1763 mL 4.3527 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1763 mL 10.8816 mL 21.7633 mL 54.4081 mL
5 mM 0.4353 mL 2.1763 mL 4.3527 mL 10.8816 mL
10 mM 0.2176 mL 1.0882 mL 2.1763 mL 5.4408 mL
15 mM 0.1451 mL 0.7254 mL 1.4509 mL 3.6272 mL
20 mM 0.1088 mL 0.5441 mL 1.0882 mL 2.7204 mL
25 mM 0.0871 mL 0.4353 mL 0.8705 mL 2.1763 mL
30 mM 0.0725 mL 0.3627 mL 0.7254 mL 1.8136 mL
40 mM 0.0544 mL 0.2720 mL 0.5441 mL 1.3602 mL
50 mM 0.0435 mL 0.2176 mL 0.4353 mL 1.0882 mL
60 mM 0.0363 mL 0.1814 mL 0.3627 mL 0.9068 mL
80 mM 0.0272 mL 0.1360 mL 0.2720 mL 0.6801 mL
100 mM 0.0218 mL 0.1088 mL 0.2176 mL 0.5441 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
WX-02-23
Cat. No.:
HY-168534
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