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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-15627
    Hoechst 33342 analog
    		98.16%
    Hoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    Hoechst 33342 analog
  • HY-15621
    DMA
    		98.89%
    DMA is a fluorescent compound (λex=340 nm, λem=478 nm).
    DMA
  • HY-D1044
    Rhodamine 101 chloride
    Rhodamine 101 chloride (Rhodamine 640 chloride) is a bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively.
    Rhodamine 101 chloride
  • HY-101937C
    (±)-ANAP hydrochloride
    (±)-ANAP hydrochloride is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
    (±)-ANAP hydrochloride
  • HY-D1042
    1,4-Dichloro 5-carboxytetramethylrhodamine
    		98.00%
    1,4-Dichloro 5-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
    1,4-Dichloro 5-carboxytetramethylrhodamine
  • HY-15619
    Hoechst S 769121
    Hoechst S 769121 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    Hoechst S 769121
  • HY-P2467
    Biotin-TAT (47-57)
    		98.56%
    Biotin-TAT (47-57), a biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used protein transduction domains (PTDs) into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis.
    Biotin-TAT (47-57)
  • HY-N0573S
    Umbelliferone-d5
    		≥98.0%
    Umbelliferone-d5 (7-Hydroxycoumarin-d5) is the deuterium labeled Umbelliferone (HY-N0573 ). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats.
    Umbelliferone-d<sub>5</sub>
  • HY-D1260
    FM-red
    		98.81%
    FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx).
    FM-red
  • HY-D1794
    Vari Fluor 405 SE
    		98.0%
    Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 405 SE
  • HY-D1622
    Cyanine3 DBCO hexafluorophosphate
    Cyanine3 DBCO (Cy3-DBCO) hexafluorophosphate is a azide reactive probe, for imaging azide-labeled biomolecules via a copper-free "click-through" reaction.
    Cyanine3 DBCO hexafluorophosphate
  • HY-D1570
    BODIPY FL C12
    		99.79%
    BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 480/508 nm.
    BODIPY FL C12
  • HY-W035214
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde is a hapten probe.
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde
  • HY-D0820
    CY5-YNE
    CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CY5-YNE
  • HY-110393
    CLR1501
    		98.62%
    CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound.
    CLR1501
  • HY-NP0181
    Maackia Amurensis Lectin II (Biotinylated)
    Maackia Amurensis Lectin II (MAL II) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin II (MAL II) Biotinylated is a biological material or organic compound that can be used in life science research.
    Maackia Amurensis Lectin II (Biotinylated)
  • HY-NP079
    Ricinus Communis Agglutinin I
    Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research.
    Ricinus Communis Agglutinin I
  • HY-W019810
    3-(Dansylamino)phenylboronic acid
    		99.03%
    3-(Dansylamino)phenylboronic acid, a phenylboronic acid derivative, can be used for the glucose detection.
    3-(Dansylamino)phenylboronic acid
  • HY-D2000
    ATTO 488
    		99.00%
    ATTO 488 is a hydrophilic rhodamine-based fluorescent dye with strong absorption and high fluorescence quantum yield. ATTO 488 is suitable for flow cytometry (FACS), fluorescence in situ hybridization (FISH) and most other labeling uses (Ex/Em: 500/520 nm).
    ATTO 488
  • HY-52112
    BCDA
    		99.80%
    BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase.
    BCDA
Cat. No. Product Name / Synonyms Application Reactivity