2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1540):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W704850
    4-Methyl PCP hydrochloride
    		Control
    4-Methyl PCP hydrochloride is an arylcyclohexylamine.
    4-Methyl PCP hydrochloride
  • HY-168814
    3α-Benzoyloxytropane hydrochloride
    3α-Benzoyloxytropane hydrochloride is a tropane.
    3α-Benzoyloxytropane hydrochloride
  • HY-124217
    Prolintane hydrochloride
    Prolintane hydrochloride, an amphetaminea, is a psychoactive compound.
    Prolintane hydrochloride
  • HY-W395204
    1-Phenylethylamine hydrochloride
    1-Phenylethylamine hydrochloride is a phenethylamine.
    1-Phenylethylamine hydrochloride
  • HY-W286489
    2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose
    		Control
    2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose is a D-glucopyranose derivative that has been used in glucosylation reactions.
    2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose
  • HY-N15054
    17-O-Demethylgeldanamycin
    17-O-Demethylgeldanamycin is a secondary metabolite that can be isolated from Streptomyces. 17-O-Demethylgeldanamycin exhibits cytotoxicity against a variety of tumor cells and has anti-tumor activity.
    17-O-Demethylgeldanamycin
  • HY-47598
    Analgesic agent-3
    Analgesic agent-3 (compound 3d) is a potent analgesic agent.
    Analgesic agent-3
  • HY-135073
    PCMPA hydrochloride
    		Control
    PCMPA hydrochloride a derivative of Phencyclidine that can be metabolized by cytochrome P450 isoenzymes (P450s).
    PCMPA hydrochloride
  • HY-W011053GL
    Neotame (GMP Like)
    Neotame (GMP Like) is the GMP Like class Neotame (HY-W011053) that can be used as pharmaceutical excipients. Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells.
    Neotame (GMP Like)
  • HY-174293
    Osimertinib dimer
    Osimertinib dimer is a dimer of Osimertinib (HY-15772). Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.
    Osimertinib dimer
  • HY-172061
    3,4-EDMC hydrochloride
    3,4-EDMC hydrochloride is designer cathinone.
    3,4-EDMC hydrochloride
  • HY-138095
    ALEPH-4
    ALEPH-4 is an analog of 2,5-Dimethoxy-4-isopropylthiophenethylamine.
    ALEPH-4
  • HY-N15387
    Hericenone J
    Hericenone J (Compound 6) is an aromatic compound with anticancer activity, which is found in Hericium erinaceum. Hericenone J is cytotoxic and can significantly reduce the viability of HL-60 human acute promyelocytic leukemia cells with an IC50 value of 4.13 μM. Hericenone J is promising for research of leukemia.
    Hericenone J
  • HY-W106785
    N-Benzylcyclohexylamine hydrochloride
    		Control
    N-Benzylcyclohexylamine hydrochloride, an arylcyclohexylamine, is a cutting agent in 3,4-MDMA samples.
    N-Benzylcyclohexylamine hydrochloride
  • HY-176010
    Dehydroepiandrosterone sulfate 17-(O-carboxymethyl)oxime sodium
    Dehydroepiandrosterone sulfate 17-(O-carboxymethyl)oxime is a derivative of dehydroepiandrosterone sulfate.
    Dehydroepiandrosterone sulfate 17-(O-carboxymethyl)oxime sodium
  • HY-170046
    Fluetizolam
    Fluetizolam (2'-Fluorodeschloroetizolam) is a thienodiazepine.
    Fluetizolam
  • HY-135030
    4-Fluoro BZP hydrochloride
    		Control
    4-Fluoro BZP hydrochloride is a benzylpiperazines (BZP) derivative. Benzylpiperazines are stimulant agents which inhibit monoamine uptake.
    4-Fluoro BZP hydrochloride
  • HY-W548095
    Anticancer agent 170
    Anticancer agent 170 (compound 3a) is a keton derivative of Deguelin (HY-13425), and shows potency anti-cancer activity against A549, with the IC50 of 6.62 μM.
    Anticancer agent 170
  • HY-148965A
    PtdIns-(3)-P1 (1,2-dipalmitoyl) ammonium
    PtdIns-(3)-P1 (1,2-dipalmitoyl) (Compound 7) ammonium is a derivative of phosphatidylinositol 3-phosphate (PtdIns(3)P). phosphatidylinositol 3-phosphate can bind to the FYVE domain of human EEA1 and act as a second messenger in cellular signaling and membrane trafficking. phosphatidylinositol 3-phosphate can stimulate ROS formation by regulating the neutrophil oxidase complex.
    PtdIns-(3)-P1 (1,2-dipalmitoyl) ammonium
  • HY-N13921
    Aphidicolin-3,18-orthoacetate
    Aphidicolin-3,18-orthoacetate is an aphidicolin derivative that inhibits the root growth of rice seedlings.
    Aphidicolin-3,18-orthoacetate