2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1342):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-112580
    SRI-31040
    SRI-31040 is an active compound.
    SRI-31040
  • HY-47601
    WAY-637940
    		≥98.0%
    WAY-637940 is an active molecule.
    WAY-637940
  • HY-119885
    Amiflamine
    Amiflamine is an active compound.
    Amiflamine
  • HY-139090
    3-Oxobetulin acetate
    3-Oxobetulin acetate (28-O-Acetyl-3-Oxobetulin; 3-oxo-28-O-Acetylbetulin) is a derivative of betulin (HY-N0083), a cholesterol biosynthesis inhibitor. 3-Oxobetulin acetate inhibits the growth of P388 murine lymphocytic leukemia cells (EC50=0.12 μg/mL) and human MCF-7 breast cancer, SF-268 CNS cancer, H460 lung cancer, and KM20L2 colon cancer cells (GI50s=8, 10.6, 5.2, and 12.7 μg/mL), but not BxPC-3 pancreatic cancer cells or DU145 prostate cancer cells (GI50s=>10 μg/mL for both). 3-Oxobetulin acetate inhibits the replication of X4-tropic recombinant HIV (NL4.3-Ren) in MT-2 lymphoblastoid cells (IC50=13.4 μM). 3-Oxobetulin acetate is also effective against Listeria donovani amastigotes.
    3-Oxobetulin acetate
  • HY-148960
    Bis(diazoacetyl)butane
    Bis(diazoacetyl)butane is an active compound.
    Bis(diazoacetyl)butane
  • HY-129672
    Thelenotoside B
    Thelenotoside B (25-Dihydrostichorrenoside E) shows strong cytotoxicities against five cancer cell lines as HepG2, KB, LNCaP, MCF7 and SK-Mel2 with the IC50 values from 0.95 ± 0.08 to 1.90 ± 0.13 μM. Thelenotoside B is a triterpene tetraglycoside.
    Thelenotoside B
  • HY-119140
    LY 116467
    LY 116467 is an active compound.
    LY 116467
  • HY-155039
    Antitumor agent-105
    Antitumor agent-105 (Compound 37) is an antitumor agent. Antitumor agent-105 has antitumor activity against A549, H1299, H460, HCT116, MDA-MB-231 cells, with IC50 values of 6.7, 8.3, 4.3, 4.4, 6.7 μM respectively.
    Antitumor agent-105
  • HY-49075
    WAY-622252
    		≥98.0%
    WAY-622252 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-622252
  • HY-129513
    SIB-1893
    SIB-1893 is an active compound.
    SIB-1893
  • HY-118464
    AC915
    AC915 is an active compound.
    AC915
  • HY-49458
    WAY-232897
    		≥98.0%
    WAY-232897 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-232897
  • HY-167931
    Cinnamohydrazide
    Cinnamohydrazide, an unsaturated carboxylic acid derivative, serves as a precursor to aspartame through enzyme-mediated amination to phenylalanine. This compound may offer potential benefits in the prevention and treatment of diabetes by facilitating insulin secretion, enhancing pancreatic β-cell function, inhibiting hepatic gluconeogenesis, promoting glucose uptake, amplifying insulin signaling pathways, delaying carbohydrate digestion and glucose absorption, and reducing protein glycation and insulin fibrillation.
    Cinnamohydrazide
  • HY-133607
    5,6-Dichlorovanillin
    5,6-Dichlorovanillin is a product upon chlorination to afford 4,5,6-trichloroguaiacol, together with tetrachloroguaiacol and the unreacted starting materials.
    5,6-Dichlorovanillin
  • HY-117984
    RU 35929
    RU 35929 is a nootropic agent. RU 35929 enhances learning and memory.
    RU 35929
  • HY-121436
    Levoxadrol
    Levoxadrol is an active enantiomer of dexoxadrol.
    Levoxadrol
  • HY-129796
    3'-Fluoroaminopterin
    3'-Fluoroaminopterin is an active compound.
    3'-Fluoroaminopterin
  • HY-119755
    Quadrosilan
    Quadrosilan is an active compound.
    Quadrosilan
  • HY-123555
    PD 142505-0028
    PD 142505-0028 is an active compound.
    PD 142505-0028
  • HY-119113
    C 175
    C 175 is a nitroacridine derivative with antitumor activity. C 175 inhibits the growth of HeLa cells monolayer (ED50=0.49 μM).
    C 175