2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1534):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118719
    Esterbut-6
    Esterbut-6 is an active compound.
    Esterbut-6
  • HY-115749A
    (Rac)-Luciferin 6′-methyl ether sodium
    D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site.
    (Rac)-Luciferin 6′-methyl ether sodium
  • HY-139247
    pNPS-DHA
    pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM.
    pNPS-DHA
  • HY-175544
    anti-TNBC agent-10
    anti-TNBC agent-10 is an anti-TNBC agent. anti-TNBC agent-10 shows potent anti-TNBC activity against BT549 cells (IC50 = 0.018 μM) and maintains activity against MDA-MB-231 cells (IC50 = 4.16 μM). anti-TNBC agent-10 9 demonstrates significant anti-tumor efficacy in mice bearing subcutaneous MDA-MB-231 TNBC xenografts. anti-TNBC agent-10 can be used for the study of triple-negative breast cancer (TNBC).
    anti-TNBC agent-10
  • HY-123043
    Afeletecan
    Afeletecan is an active compound.
    Afeletecan
  • HY-121936R
    Yohimbic acid (Standard)
    Hexyl methanesulfonate (Standard) is the analytical standard of Hexyl methanesulfonate. This product is intended for research and analytical applications. Hexyl methanesulfonate (Methanesulfonic acid hexyl ester) is an ester product.
    Yohimbic acid (Standard)
  • HY-115950
    Antitumor agent-48
    Antitumor agent-48 (Compound 4a) is a 2,3-dehydrosilybin derivative with an antitumor activity. Antitumor agent-48 shows cytotoxic activity against MCF-7, NCI-H1299, HepG2 and HT29 cells with IC50 values of 8.06 µM, 13.1 µM, 16.51 µM and 12.44 µM, respectively.
    Antitumor agent-48
  • HY-W002304R
    (R)-5-Oxopyrrolidine-2-carboxylic acid (Standard)
    (R)-5-Oxopyrrolidine-2-carboxylic acid (Standard) is the analytical standard of (R)-5-Oxopyrrolidine-2-carboxylic acid (HY-W002304). This product is intended for research and analytical applications. (R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of D-glutamate. (R)-5-Oxopyrrolidine-2-carboxylic acid can be used in the research of metabolic syndrome and end-stage renal disease.
    (R)-5-Oxopyrrolidine-2-carboxylic acid (Standard)
  • HY-116897
    G202-0362
    G202-0362 is an active compound.
    G202-0362
  • HY-N15447
    Visnaginone
    Visnaginone is the derivative of Visnagin (HY-N1082). Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles.
    Visnaginone
  • HY-157073
    WAY-607695
    		98.0%
    WAY-607695 is an active molecule.
    WAY-607695
  • HY-105577
    Picilorex
    Picilorex is an active compound. Picilorex can be used for the research of anorectic.
    Picilorex
  • HY-105641
    Morazone
    Morazone is a non-steroidal anti-inflammatory drug (NSAID).
    Morazone
  • HY-118555
    Vascular disrupting agent 1
    Vascular disrupting agent 1 is an active compound.
    Vascular disrupting agent 1
  • HY-124100
    LTB4 antagonist 4
    LTB4 antagonist 4 is an active compound.
    LTB4 antagonist 4
  • HY-W004292S
    1-Undecanol-d23
    1-Undecanol-d23 (Undecyl alcohol-d23) is the deuterium labeled 1-Undecanol (HY-W004292). 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps.
    1-Undecanol-d<sub>23</sub>
  • HY-145673
    Thiamphenicol glycinate
    Thiamphenicol glycinate, an alpha-amino acid ester, is a proagent of Thiamphenicol (HY-B0479).
    Thiamphenicol glycinate
  • HY-E70242
    3-Ketohexanoyl-CoA
    3-Ketohexanoyl-CoA is a derivative of coenzyme A containing a ketone group.
    3-Ketohexanoyl-CoA
  • HY-133601
    3,4,5-Trichloroguaiacol
    3,4,5-Trichloroguaiacol is a phenolic compound occurring in effluents from bleached kraft pulp mills.
    3,4,5-Trichloroguaiacol
  • HY-129932
    Pyrrolidine ricinoleamide
    Pyrrolidine ricinoleamide ((R)-5d) is a fatty acid amide that exhibits effective antiproliferative activity against a series of cancer cells, including human glioma U251 cells. Pyrrolidine ricinoleamide can be used in cancer research.
    Pyrrolidine ricinoleamide