2. Signaling Pathways
  3. Immunology/Inflammation
  4. Cyclic GMP-AMP Synthase
  5. Cyclic GMP-AMP Synthase Agonist

Cyclic GMP-AMP Synthase Agonist

Cyclic GMP-AMP Synthase Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-W587488
    Adenosine 3′-monophosphate
    		Agonist 99%
    Adenosine 3’-monophosphate (3’-AMP) is a nucleotide. Adenosine 3’-monophosphate is a cyclic AMP production agonist. Adenosine 3’-monophosphate increases cyclic AMP levels concentration-dependently in NG108-15 cells. Adenosine 3’-monophosphate can be used in the determination of acid phosphatase activity of human serum, which is estabilished as a laboratory procedure in the diagnosis of prostate cancer, metastatic mammary cancer and Gaucher’s disease. Adenosine 3’-monophosphate inhibits human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors.
  • HY-171692
    G3-YSD
    		Agonist
    G3-YSD, a G3-ended Y-form short DNA, is a Cyclic GMP-AMP synthase (cGAS) agonist. G3-YSD is a minimal immunostimulatory DNA motif and activates the type I interferon-inducing DNA sensor cGAS in a structure-and sequence-dependent manner. G3-YSD can be used for the detection of HIV-1 ssDNA.