2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-15308
    Avermectin B1a
    		98.26%
    Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a
  • HY-A0246A
    Flucloxacillin sodium
    		98.03%
    Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria.
    Flucloxacillin sodium
  • HY-17010
    Retapamulin
    		≥98.0%
    Retapamulin (SB-275833) is a topical antibiotic that binds Staphylococcus aureus and E. coli ribosomes with a Kd of 3 nM. Retapamulin can be used in researches of atopic dermatitis and prostate cancer.
    Retapamulin
  • HY-B1078
    Cefazolin sodium
    		98.45%
    Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
    Cefazolin sodium
  • HY-17566
    Capreomycin sulfate
    		99.52%
    Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. Capreomycin sulfate has anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting the occurrence of amyloid fibrillation. Capreomycin sulfate can be used in the study of multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease and Parkinson's disease.
    Capreomycin sulfate
  • HY-10392
    Sutezolid
    		99.40%
    Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis.
    Sutezolid
  • HY-B1071A
    Lasalocid sodium
    		98.28%
    Lasalocid sodium (Lasalocid sodium-A) is an antibacterial and anticoccidial agent that can be used as feed additives. Lasalocid sodium exhibits antitumor activity. Lasalocid sodium is orally active.
    Lasalocid sodium
  • HY-B0277
    Vidarabine
    		99.35%
    Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses. Vidarabine has IC50s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2. Vidarabine also has anti-orthopoxvirus activity.
    Vidarabine
  • HY-116010
    Oleandomycin
    		99.84%
    Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes.
    Oleandomycin
  • HY-100593
    Spiramycin
    		98.56%
    Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached.
    Spiramycin
  • HY-B1350A
    Fusidic acid sodium salt
    		99.64%
    Fusidic acid sodium salt is an orally available antibacterial agent that inhibits bacterial protein synthesis by preventing the release of translation elongation factor G (EF-G) from ribosomes. Fusidic acid sodium salt inhibits the inhibitory and activating effects of interleukins IL-1 and IL-6 on glucose-induced insulin production and exhibits antidiabetic effects in a rat model. Fusidic acid sodium salt improves the symptoms of colitis in rats and inhibits the growth of Toxoplasma gondii and Listeria monocytogenes EGD in vitro, but not in mice.
    Fusidic acid sodium salt
  • HY-B0535
    Ethambutol
    		≥98.0%
    Ethambutol is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. Ethambutol can be used to establish animal models of hyperuricemia and optic neuropathy.
    Ethambutol
  • HY-P0270
    Magainin 2
    		98.92%
    Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa. Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes.
    Magainin 2
  • HY-B0454A
    Miconazole nitrate
    		99.75%
    Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects.
    Miconazole nitrate
  • HY-17560
    Demeclocycline hydrochloride
    Demeclocycline hydrochloride is a tetracycline antibiotic; is an antibiotic in the treatment of Lyme disease, acne, and bronchitis.
    Demeclocycline hydrochloride
  • HY-N6779
    Patulin
    		99.47%
    Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage.
    Patulin
  • HY-17624A
    Framycetin sulfate
    		≥98.0%
    Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.
    Framycetin sulfate
  • HY-B1175
    (2S,5R,6R)-Ticarcillin disodium
    		98.15%
    (2S,5R,6R)-Ticarcillin disodium is a semisynthetic antibiotic with bactericidal activities. (2S,5R,6R)-Ticarcillin disodium is the (2S,5R,6R)-enantiomer of Ticarcillin (HY-139805).
    (2S,5R,6R)-Ticarcillin disodium
  • HY-128423
    Tylvalosin tartrate
    		98.77%
    Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation.
    Tylvalosin tartrate
  • HY-13573
    Biapenem
    		≥98.0%
    Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum.
    Biapenem
Antibiotic Isoform Comparison

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