2. Signaling Pathways
  3. GPCR/G Protein
  4. Amylin Receptor
  5. Amylin Receptor Agonist

Amylin Receptor Agonist

Amylin Receptor Agonists (8):

Cat. No. Product Name Effect Purity
  • HY-P10798
    Eloralintide
    		Agonist 99.97%
    Eloralintide (LY 3841136) is an AMYR agonist, which is promising for research of type 2 diabetes and obesity.
  • HY-P11245A
    NN1213 acetate
    		Agonist 99.65%
    NN1213 acetate (Peptide 21), a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with an EC50 of 0.177 and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 acetate significantly reduces appetite in rat and dog models. NN1213 acetate can be used for antiobesity research.
  • HY-P10956
    Colulintide
    		Agonist 98.35%
    Colulintide is a functional analog of amylin that can be used in obesity research.
  • HY-P11274A
    Zenagamtide sodium
    		Agonist
    Zenagamtide is a glucagon-like peptide (GLP-1) and amylin receptors agonist.
  • HY-P11274
    Zenagamtide
    		Agonist
    Zenagamtide is a glucagon-like peptide (GLP-1) and amylin receptors agonist.
  • HY-P11320
    Davalintide
    		Agonist
    Davalintide is an Amylin (HY-P1464)-mimetic peptide with greater potency and longer-lasting effects. Davalintide is a potent agonist of amylin receptor (IC50 = 0.04 nM), calcitonin receptor (IC50 = 0.06 nM) and calcitonin related peptide receptor (CGRP receptor) (IC50 = 3.1 nM). Davalintide shows stronger potency to Amylin to activate cyclic AMP production through the calcitonin receptor (EC50 = 1.4 nM). Davalintide regulates blood sugar and weight through various mechanisms such as delaying gastric emptying, inhibiting glucagon secretion, and reducing food intake. Davalintide can be used for the studies of anti-obesity and anti-diabetes.
  • HY-P11269
    Lenbelintide
    		Agonist
    Lenbelintide is a dual amylin/calcitonin receptor agonist. Lenbelintide can be studied in research on obesity.
  • HY-P11245
    NN1213
    		Agonist
    NN1213 (Peptide 21), a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with an EC50 of 0.177 and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 significantly reduces appetite in rat and dog models. NN1213 can be used for antiobesity research.